product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat Anti-Neutrophil Elastase Antibody ELISA Kit
catalog :
MBS724898
quantity :
96 Strip Wells
price :
675 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS724898
products type :
ELISA Kit
products full name :
Rat Anti-Neutrophil Elastase Antibody ELISA Kit
products short name :
Anti-Neutrophil Elastase Antibody
other names :
neutrophil elastase, partial; Neutrophil elastase; neutrophil elastase; elastase-2; medullasin; PMN elastase; leukocyte elastase; elastase 2, neutrophil; human leukocyte elastase; polymorphonuclear elastase; bone marrow serine protease; granulocyte-derived elastase; elastase, neutrophil expressed; Bone marrow serine protease; Elastase-2; Human leukocyte elastase; HLE; Medullasin; PMN elastase
products gene name :
ANEA
other gene names :
ELANE; ELANE; GE; NE; HLE; HNE; ELA2; SCN1; PMN-E; ELA2; HLE
uniprot entry name :
ELNE_HUMAN
reactivity :
Rat
storage stability :
Store all reagents at 2-8 degree C.
products categories :
Neurobiology
ncbi gi num :
386981
ncbi acc num :
AAA36359.1
ncbi mol weight :
28,518 Da
ncbi pathways :
Activation Of Matrix Metalloproteinases Pathway 576264!!C-MYB Transcription Factor Network Pathway 138073!!Collagen Degradation Pathway 730309!!Degradation Of The Extracellular Matrix Pathway 576263!!Extracellular Matrix Organization Pathway 576262!!Systemic Lupus Erythematosus Pathway 83122!!Systemic Lupus Erythematosus Pathway 534!!Transcriptional Misregulation In Cancer Pathway 523016!!Transcriptional Misregulation In Cancer Pathway 522987!!Amb2 Integrin Signaling Pathway 137945
ncbi summary :
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins. The product of this gene hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is clustered with other serine protease gene family members, azurocidin 1 and proteinase 3 genes, at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, May 2009]
size :
96 Strip Wells
price :
675 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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