catalog number :
MBS724742
products type :
ELISA Kit
products full name :
Human Activating Transcription Factor 2 ELISA Kit
products short name :
Activating Transcription Factor 2
other names :
ATF2 protein; Cyclic AMP-dependent transcription factor ATF-2; cyclic AMP-dependent transcription factor ATF-2; histone acetyltransferase ATF2; cAMP-dependent transcription factor ATF-2; cAMP-responsive element-binding protein 2; cAMP response element-binding protein CRE-BP1; cyclic AMP-responsive element-binding protein 2; cAMP responsive element binding protein 2, formerly; activating transcription factor 2 splice variant ATF2-var2; activating transcription factor 2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding protein 2; HB16; Histone acetyltransferase ATF2; cAMP response element-binding protein CRE-BP1
products gene name :
ATF2
other gene names :
ATF2; ATF2; HB16; CREB2; TREB7; CREB-2; CRE-BP1; CREB2; CREBP1; cAMP-dependent transcription factor ATF-2; CREB-2; cAMP-responsive element-binding protein 2
uniprot entry name :
ATF2_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
products categories :
Epigenetics and Nuclear Signaling
ncbi acc num :
AAH26175.1
ncbi mol weight :
15,409 Da
ncbi pathways :
AGE/RAGE Pathway 698754!!ATF-2 Transcription Factor Network Pathway 138006!!Activated TLR4 Signalling Pathway 106400!!Activation Of The AP-1 Family Of Transcription Factors Pathway 160139!!Adrenergic Signaling In Cardiomyocytes Pathway 908257!!Adrenergic Signaling In Cardiomyocytes Pathway 909696!!Alcoholism Pathway 585563!!Alcoholism Pathway 587116!!Amphetamine Addiction Pathway 547607!!Amphetamine Addiction Pathway 550546
ncbi summary :
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]