Human Cyclin D1 ELISA Kit | MyBioSource MBS724349 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Cyclin D1 ELISA Kit

catalog :

MBS724349

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS724349

products type :

ELISA Kit

products full name :

Human Cyclin D1 ELISA Kit

products short name :

Cyclin D1

other names :

CCND1, partial; CCND1 protein; G1/S-specific cyclin-D1; BCL-1 oncogene; PRAD1 oncogene; B-cell CLL/lymphoma 1; B-cell lymphoma 1 protein; cyclin D1; CCND1 protein; Cyclin D1 (PRAD1: parathyroid adenomatosis 1); Cyclin D1, isoform CRA_c; cDNA, FLJ93625, Homo sapiens cyclin D1 (PRAD1: parathyroid adenomatosis 1) (CCND1),mRNA

products gene name :

CCND1

other gene names :

CCND1; CCND1; BCL1; PRAD1; U21B31; D11S287E; hCG_2016647

uniprot entry name :

Q6FI00_HUMAN

reactivity :

Human

storage stability :

Store all reagents at 2-8 degree C.

other info1 :

Assay Type: Competitive

other info2 :

Highest Standards: 25ng/mL. Concentration of Standards: Concentration of Standards: 0,1,2.5,5.0,10,25ng/mL

products categories :

Cell Biology

ncbi gi num :

49457151

ncbi acc num :

CAG46896.1

uniprot acc num :

Q6FI00

ncbi mol weight :

33,729 Da

ncbi pathways :

AMPK Signaling Pathway (989139); AMPK Signaling Pathway (992181); ATF-2 Transcription Factor Network Pathway (138006); Acute Myeloid Leukemia Pathway (83117); Acute Myeloid Leukemia Pathway (529); Androgen Receptor Signaling Pathway (198806); Bladder Cancer Pathway (83115); Bladder Cancer Pathway (527); C-MYB Transcription Factor Network Pathway (138073); Cell Cycle Pathway (530733)

ncbi summary :

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008]

uniprot summary :

CCND1: a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Protein type: Oncoprotein; Nuclear receptor co-regulator; Cell cycle regulation; Activator. Chromosomal Location of Human Ortholog: 11q13. Cellular Component: nucleoplasm; tight junction; membrane; transcriptional repressor complex; cyclin-dependent protein kinase holoenzyme complex; intracellular; cytosol; nucleus. Molecular Function: protein binding; enzyme binding; histone deacetylase binding; protein complex binding; cyclin-dependent protein kinase regulator activity; protein kinase binding; transcription corepressor activity; transcription factor binding; protein kinase activity. Biological Process: fat cell differentiation; G1 DNA damage checkpoint; lactation; establishment and/or maintenance of chromatin architecture; positive regulation of cyclin-dependent protein kinase activity; re-entry into mitotic cell cycle; negative regulation of Wnt receptor signaling pathway; positive regulation of mammary gland epithelial cell proliferation; negative regulation of epithelial cell differentiation; Wnt receptor signaling pathway through beta-catenin; negative regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; response to vitamin E; response to magnesium ion; Leydig cell differentiation; response to iron ion; response to X-ray; response to corticosterone stimulus; response to drug; organ regeneration; Notch signaling pathway; transcription, DNA-dependent; unfolded protein response; mammary gland epithelial cell proliferation; liver development; response to organic nitrogen; response to ethanol; response to estrogen stimulus; cell division; mitotic cell cycle; positive regulation of protein amino acid phosphorylation; response to calcium ion; response to DNA damage stimulus; G1/S transition of mitotic cell cycle. Disease: Von Hippel-lindau Syndrome; Myeloma, Multiple

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

675

more info or order :

MyBioSource product webpage