catalog number :
MBS7240908
products type :
ELISA Kit
products full name :
Mouse Translocation protein SEC62 (SEC62) ELISA Kit
products short name :
Translocation protein SEC62 (SEC62)
other names :
translocation protein SEC62; Translocation protein SEC62; translocation protein SEC62; hTP-1; translocation protein 1; membrane protein SEC62, S.cerevisiae, homolog of; SEC62 homolog (S. cerevisiae); Translocation protein 1; TP-1; hTP-1
products gene name :
SEC62
other gene names :
SEC62; SEC62; HTP1; TP-1; Dtrp1; TLOC1; TLOC1; TP-1; hTP-1
uniprot entry name :
SEC62_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
products categories :
Epigenetics and Nuclear Signaling
ncbi acc num :
NP_003253.1
ncbi gb acc num :
NM_003262.3
ncbi mol weight :
45,862 Da
ncbi pathways :
Protein Export Pathway (83041); Protein Export Pathway (446); Protein Processing In Endoplasmic Reticulum Pathway (167325); Protein Processing In Endoplasmic Reticulum Pathway (167190)
ncbi summary :
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
uniprot summary :
SEC62: a multi-pass membrane protein and component of the Sec61 complex of the rough endoplasmic reticulum membrane. The Sec61 complex may perform post-translational protein translocation into the ER and backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. Protein type: Membrane protein, multi-pass; Endoplasmic reticulum; Membrane protein, integral; Channel, misc. Chromosomal Location of Human Ortholog: 3q26.2. Cellular Component: endoplasmic reticulum membrane; intermediate filament cytoskeleton; rough endoplasmic reticulum; membrane; endoplasmic reticulum; integral to membrane. Molecular Function: receptor activity; protein transporter activity. Biological Process: posttranslational protein targeting to membrane; cotranslational protein targeting to membrane