catalog number :
MBS723651
products type :
ELISA Kit
products full name :
Mouse Glial Fibrillary Acidic Protein ELISA Kit
products short name :
[Glial Fibrillary Acidic Protein]
other names :
[glial fibrillary acidic protein; Glial fibrillary acidic protein; glial fibrillary acidic protein; glial fibrillary acidic protein]
products gene name :
[GFAP]
other gene names :
[GFAP; GFAP; GFAP]
uniprot entry name :
GFAP_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of GFAP. No significant cross-reactivity or interference between GFAP and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection between GFAP and all the analogues, therefore, cross reaction may still exist in some cases.
storage stability :
Store all reagents at 2-8 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, plasma, cell culture supernatants, body fluid and tissue homogenate. Sensitivity: 1.0 pg/mL
products categories :
Neurobiology
products description :
Intended Uses: This BG GFAP ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Mouse GFAP. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
ncbi acc num :
AAB22581.1
ncbi mol weight :
49,508 Da
ncbi pathways :
Neural Crest Differentiation Pathway (672460); Nuclear Signaling By ERBB4 Pathway (530744); Signal Transduction Pathway (477114); Signaling By ERBB4 Pathway (530741); Spinal Cord Injury Pathway (739007)
ncbi summary :
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
uniprot summary :
GFAP: a class-III intermediate filament protein. A cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant isoform has been described, but its full length sequence has not been determined. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 17q21. Cellular Component: membrane; cytoplasm; intermediate filament; cytosol. Molecular Function: integrin binding; structural constituent of cytoskeleton; kinase binding. Biological Process: extracellular matrix organization and biogenesis; Bergmann glial cell differentiation; regulation of neurotransmitter uptake; response to wounding; neurite regeneration; intermediate filament organization; astrocyte development. Disease: Alexander Disease
size4 :
10x96-Strip-Wells