product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human 1 phosphatidylinositol 4, 5 bisphosphate phosphodiesterase delta 4 ELISA Kit
catalog :
MBS723031
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS723031
products type :
ELISA Kit
products full name :
Human 1 phosphatidylinositol 4, 5 bisphosphate phosphodiesterase delta 4 ELISA Kit
products short name :
1 phosphatidylinositol 4, 5 bisphosphate phosphodiesterase delta 4
other names :
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4; PLC delta4; phosphoinositide phospholipase C-delta-4; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4; phospholipase C, delta 4; Phosphoinositide phospholipase C-delta-4; Phospholipase C-delta-4; PLC-delta-4
products gene name :
PLCD4
other gene names :
PLCD4; PLCD4; hPLCD4; PLC-delta-4
uniprot entry name :
PLCD4_HUMAN
reactivity :
Human
storage stability :
Store all reagents at 2-8 degree C.
products categories :
Cancer
ncbi gi num :
74732863
ncbi acc num :
Q9BRC7.1
ncbi mol weight :
31,448 Da
ncbi pathways :
Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway (545326); D-myo-inositol-5-phosphate Metabolism Pathway (545315); Inositol Phosphate Metabolism Pathway (82987); Inositol Phosphate Metabolism Pathway (362); Inositol Phosphate Metabolism, PI= PIP2 = Ins(1,4,5)P3 = Ins(1,3,4,5)P4 Pathway (413400); Inositol Phosphate Metabolism, PI= PIP2 = Ins(1,4,5)P3 = Ins(1,3,4,5)P4 Pathway (468323); Metabolic Pathways (132956); Phosphatidylinositol Signaling System Pathway (83052)
ncbi summary :
This gene encodes a member of the delta class of phospholipase C enzymes. Phospholipase C enzymes play a critical role in many cellular processes by hydrolyzing phosphatidylinositol 4,5-bisphosphate into two intracellular second messengers, inositol 1,4,5-trisphosphate and diacylglycerol. Expression of this gene may be a marker for cancer. [provided by RefSeq, Jan 2011]
uniprot summary :
PLCD4: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida- induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Phospholipase; EC 3.1.4.11; Carbohydrate Metabolism - inositol phosphate. Chromosomal Location of Human Ortholog: 2q35. Cellular Component: nuclear membrane; endoplasmic reticulum; cytoplasm; plasma membrane. Molecular Function: signal transducer activity; calcium ion binding; phosphoinositide phospholipase C activity. Biological Process: acrosome reaction; phosphatidylinositol metabolic process; lipid catabolic process
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
675
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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