catalog number :
MBS722815
products type :
ELISA Kit
products full name :
Rat alpha Synuclein ELISA Kit
products short name :
alpha Synuclein
products name syn :
Rat a Synuclein ELISA Kit
other names :
alpha-synuclein; Alpha-synuclein; alpha-synuclein; non-A4 component of amyloid; non-A beta component of AD amyloid; synuclein, alpha; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP
products gene name :
alpha-SYN
products gene name syn :
a-SYN
other gene names :
Snca; Snca; NACP; alphaSYN; Syn; NACP
uniprot entry name :
SYUA_MOUSE
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Assay Type: Competitive
other info2 :
Highest Standards: 25ng/mL. Concentration of Standards: Concentration of Standards: 0,1.0,2.5,5.0,10,25ng/mL
products categories :
Neurobiology
ncbi acc num :
NP_001035916.1
ncbi gb acc num :
NM_001042451.2
ncbi mol weight :
12,345 Da
ncbi pathways :
Alzheimer's Disease Pathway (83294); Alzheimer's Disease Pathway (509); Amyloids Pathway (1000612); Disease Pathway (970606); EGFR1 Signaling Pathway (198278); Parkinson's Disease Pathway (83295)
uniprot summary :
SNCA: a member of the synuclein family. Abundantly expressed in the brain. Inhibits phospholipase D2 selectively. May integrate presynaptic signaling and membrane trafficking. Implicated in the pathogenesis of Parkinson s disease. A major component of amyloid plaques in the brains of patients with Alzheimer s disease. Two alternatively spliced isoforms transcripts have been identified. Protein type: Adaptor/scaffold. Cellular Component: Golgi apparatus; nuclear outer membrane; cytoplasmic vesicle membrane; intracellular membrane-bound organelle; mitochondrion; rough endoplasmic reticulum; cell; fibril; terminal button; inclusion body; cell cortex; cytosol; actin cytoskeleton; synaptic vesicle; platelet alpha granule membrane; cytoskeleton; growth cone; perinuclear region of cytoplasm; axon; cytoplasm; plasma membrane; ribosome; synapse; nerve terminal; nucleus. Molecular Function: protein domain specific binding; identical protein binding; zinc ion binding; histone binding; kinesin binding; microtubule binding; ferrous iron binding; metal ion binding; caspase inhibitor activity; magnesium ion binding; beta-tubulin binding; protein N-terminus binding; phosphoprotein binding; calcium ion binding; oxidoreductase activity; Hsp70 protein binding; arachidonic acid binding; dynein binding; protein binding; copper ion binding; phospholipase binding; enzyme binding; phospholipid binding; tau protein binding; alpha-tubulin binding. Biological Process: regulation of acyl-CoA biosynthetic process; adult locomotory behavior; regulation of neurotransmitter secretion; positive regulation of endocytosis; response to lipopolysaccharide; dopamine biosynthetic process; dopamine metabolic process; positive regulation of neurotransmitter secretion; response to magnesium ion; regulation of neuron apoptosis; synapse organization and biogenesis; negative regulation of neuron apoptosis; response to drug; negative regulation of dopamine metabolic process; synaptic vesicle endocytosis; negative regulation of transporter activity; regulation of neuronal synaptic plasticity; negative regulation of apoptosis; regulation of long-term neuronal synaptic plasticity; negative regulation of serotonin uptake; synaptic transmission, dopaminergic; mitochondrial membrane organization and biogenesis; negative regulation of norepinephrine uptake; microglial cell activation; negative regulation of caspase activity; negative regulation of monooxygenase activity; fatty acid metabolic process; regulation of dopamine secretion; positive regulation of synaptic transmission; negative regulation of histone acetylation; negative regulation of dopamine uptake; synaptic transmission; negative regulation of exocytosis; negative regulation of protein amino acid phosphorylation; behavioral response to cocaine; receptor internalization; phospholipid metabolic process; response to iron(II) ion; positive regulation of receptor recycling; caspase activation; neutral lipid metabolic process; protein destabilization; negative regulation of microtubule polymerization; regulation of glutamate secretion; regulation of macrophage activation; synaptic vesicle transport; positive regulation of peptidyl-serine phosphorylation; organelle ATP synthesis coupled electron transport; regulation of locomotion; positive regulation of release of sequestered calcium ion into cytosol; regulation of excitatory postsynaptic membrane potential