product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Collagen Type X ELISA Kit
catalog :
MBS722660
quantity :
48-Strip-Wells-(Comp
price :
470 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS722660
products type :
ELISA Kit
products full name :
Human Collagen Type X ELISA Kit
products short name :
Collagen Type X
other names :
collagen alpha-1(X) chain; Collagen alpha-1(X) chain; collagen alpha-1(X) chain; collagen alpha-1(X) chain; collagen X, alpha-1 polypeptide; Schmid metaphyseal chondrodysplasia; collagen, type X, alpha 1
products gene name :
COL10
other gene names :
COL10A1; COL10A1
uniprot entry name :
COAA1_HUMAN
reactivity :
Human
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Assay Type: Competitive or Sandwich
other info2 :
Highest Standards: 25ng/mL. Concentration of Standards: Concentration of Standards: 0,1,2.5,5.0,10,25ng/mL
products categories :
Cell Biology
ncbi gi num :
18105032
ncbi acc num :
NP_000484.2
ncbi gb acc num :
NM_000493.3
ncbi mol weight :
66,158 Da
ncbi pathways :
Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (730306); Collagen Biosynthesis And Modifying Enzymes Pathway (645289); Collagen Formation Pathway (645288); Endochondral Ossification Pathway (198812); Extracellular Matrix Organization Pathway (576262); Senescence And Autophagy Pathway (198780)
ncbi summary :
This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD). [provided by RefSeq, Jul 2008]
uniprot summary :
COL10A1: Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage. Defects in COL10A1 are the cause of Schmid type metaphyseal chondrodysplasia (SMCD). SMCD is a dominantly inherited disorder of the osseous skeleton. The cardinal features of the phenotype are mild short stature, coxa vara and a waddling gait. Radiography usually shows sclerosis of the ribs, flaring of the metaphyses, and a wide irregular growth plate, especially of the knees. A variant form of SMCD is spondylometaphyseal dysplasia Japanese type. It is characterized by spinal involvement comprising mild platyspondyly, vertebral body abnormalities, and end-plate irregularity. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 6q21-q22. Cellular Component: proteinaceous extracellular matrix; collagen; endoplasmic reticulum lumen; extracellular region; cell cortex. Molecular Function: metal ion binding. Biological Process: extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis; cartilage development; skeletal development; endochondral ossification. Disease: Metaphyseal Chondrodysplasia, Schmid Type
size1 :
48-Strip-Wells-(Competitive)
price1 :
470 USD
size2 :
48-Strip-Wells-(Sandwich)
price2 :
470
size3 :
96-Strip-Wells-(Competitive)
price3 :
675
size4 :
96-Strip-Wells-(Sandwich)
price4 :
675
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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