Human C C motif chemokine 26 (CCL26) ELISA Kit | MyBioSource MBS7226524 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human C C motif chemokine 26 (CCL26) ELISA Kit

catalog :

MBS7226524

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS7226524

products type :

ELISA Kit

products full name :

Human C C motif chemokine 26 (CCL26) ELISA Kit

products short name :

C C motif chemokine 26 (CCL26)

other names :

C-C motif chemokine 26; C-C motif chemokine 26; C-C motif chemokine 26; eotaxin-3; MIP-4-alpha; chemokine N1; CC chemokine IMAC; thymic stroma chemokine-1; small inducible cytokine A26; small-inducible cytokine A26; macrophage inflammatory protein 4-alpha; small inducible cytokine subfamily A (Cys-Cys), member 26; chemokine (C-C motif) ligand 26; CC chemokine IMAC; Eotaxin-3; Macrophage inflammatory protein 4-alpha; MIP-4-alpha; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1

products gene name :

CCL26

other gene names :

CCL26; CCL26; IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha; SCYA26; UNQ216/PRO242; MIP-4-alpha; TSC-1

uniprot entry name :

CCL26_HUMAN

reactivity :

Human

specificity :

This assay has high sensitivity and excellent specificity for detection of CCL-26. No significant cross-reactivity or interference between CCL-26 and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection between CCL-26 and all the analogues, therefore, cross reaction may still exist in some cases.

storage stability :

Store all reagents at 2-8 degree C.

other info1 :

Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Assay Type: Competitive. Sensitivity: 1.0 pg/mL.

other info2 :

Intended Uses: This CCL-26 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Human CCL-26. This ELISA kit for research use only, not for therapeutic or diagnostic applications!

products categories :

Immunology

products description :

Principle of the assay: CCL-26 ELISA kit applies the competitive enzyme immunoassay technique utilizing a monoclonal anti-CCL-26 antibody and an CCL-26-HRP conjugate. The assay sample and buffer are incubated together with CCL-26-HRP conjugate in pre-coated plate for one hour. After the incubation period, the wells are decanted and washed five times. The wells are then incubated with a substrate for HRP enzyme. The product of the enzyme-substrate reaction forms a blue colored complex. Finally, a stop solution is added to stop the reaction, which will then turn the solution yellow. The intensity of color is measured spectrophotometrically at 450nm in a microplate reader. The intensity of the color is inversely proportional to the CCL-26 concentration since CCL-26 from samples and CCL-26-HRP conjugate compete for the anti-CCL-26 antibody binding site. Since the number of sites is limited, as more sites are occupied by CCL-26 from the sample, fewer sites are left to bind CCL-26-HRP conjugate. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The CCL-26 concentration in each sample is interpolated from this standard curve.

ncbi gi num :

5174671

ncbi acc num :

NP_006063.1

ncbi gb acc num :

NM_006072.4

ncbi mol weight :

10,648 Da

ncbi pathways :

Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); IL4-mediated Signaling Events Pathway (137933)

ncbi summary :

This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008]

uniprot summary :

CCL26: Chemotactic for eosinophils and basophils. Binds to CCR3. Belongs to the intercrine beta (chemokine CC) family. Protein type: Chemokine; Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 7q11.23. Cellular Component: extracellular space. Molecular Function: chemokine activity. Biological Process: positive regulation of actin filament polymerization; cell-cell signaling; positive regulation of endothelial cell proliferation; immune response; inflammatory response; signal transduction; chemotaxis; positive regulation of cell migration

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

675

more info or order :

MyBioSource product webpage