ELISA/assay

Human 1 phosphatidylinositol 4, 5 bisphosphate phosphodiesterase beta 1 ELISA Kit

MBS7226163

48-Strip-Wells

470 USD

ELISA Kit

Human 1 phosphatidylinositol 4, 5 bisphosphate phosphodiesterase beta 1 ELISA Kit

1 phosphatidylinositol 4, 5 bisphosphate phosphodiesterase beta 1

Human 1 phosphatidylinositol 4, 5 bisphosphate phosphodiesterase b 1 ELISA Kit

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1; PLC-beta-1; phospholipase C-I; phosphoinositidase C; inositoltrisphosphohydrolase; triphosphoinositide phosphodiesterase; monophosphatidylinositol phosphodiesterase; 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; phospholipase C, beta 1 (phosphoinositide-specific); PLC-154; Phosphoinositide phospholipase C-beta-1; Phospholipase C-I; PLC-I; Phospholipase C-beta-1; PLC-beta-1

PLCB1

PLCB1

PLCB1; PLCB1; PLC-I; EIEE12; PI-PLC; PLC154; PLCB1A; PLCB1B; PLC-154; KIAA0581; PLC-I; PLC-beta-1

PLCB1_HUMAN

Human

Store all reagents at 2-8 degree C.

Signal Transduction

12083581

NP_056007.1

NM_015192.3

133,703 Da

AMPK Signaling Pathway (198868); Acetylcholine Regulates Insulin Secretion Pathway (105924); Activation Of Kainate Receptors Upon Glutamate Binding Pathway (161043); Adrenergic Signaling In Cardiomyocytes Pathway (908257); Adrenergic Signaling In Cardiomyocytes Pathway (909696); African Trypanosomiasis Pathway (194384); African Trypanosomiasis Pathway (194323); Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448)

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

PLCB1: an enzyme that catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. Binds to calmodulin. Uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. Activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variant isoforms have been described. Protein type: Phospholipase; Carbohydrate Metabolism - inositol phosphate; EC 3.1.4.11. Chromosomal Location of Human Ortholog: 20p12. Cellular Component: nuclear membrane; cytoplasm; nuclear chromatin; nuclear speck; nucleus; cytosol. Molecular Function: calmodulin binding; signal transducer activity; phosphatidylinositol-4,5-bisphosphate binding; enzyme binding; protein homodimerization activity; calcium ion binding; phosphoinositide phospholipase C activity; GTPase activator activity; lamin binding. Biological Process: fat cell differentiation; positive regulation of developmental growth; acetylcholine receptor signaling, muscarinic pathway; inositol phosphate metabolic process; positive regulation of interleukin-12 production; glutamate signaling pathway; metabolic process; positive regulation of transcription, DNA-dependent; positive regulation of JNK cascade; signal transduction; memory; positive regulation of myoblast differentiation; synaptic transmission; positive regulation of embryonic development; insulin-like growth factor receptor signaling pathway; cerebral cortex development; phosphatidylinositol metabolic process; negative regulation of transcription, DNA-dependent; G2/M transition of mitotic cell cycle; lipid catabolic process; regulation of G-protein coupled receptor protein signaling pathway; positive regulation of GTPase activity. Disease: Epileptic Encephalopathy, Early Infantile, 12

48-Strip-Wells

470 USD

96-Strip-Wells

675