Mouse Placental Lactogen ELISA Kit | MyBioSource MBS722598 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Placental Lactogen ELISA Kit

catalog :

MBS722598

quantity :

48-Strip-Wells-(Comp

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS722598

products type :

ELISA Kit

products full name :

Mouse Placental Lactogen ELISA Kit

products short name :

Placental Lactogen

other names :

placental lactogen; Chorionic somatomammotropin hormone 1; chorionic somatomammotropin hormone 1; choriomammotropin; placental lactogen; chorionic somatomammotropin A; chorionic somatomammotropin-1; chorionic somatomammotropin hormone 1 (placental lactogen); Lactogen; Placental lactogen; PL

products gene name :

other gene names :

CSH1; CSH1; PL; CSA; CS-1; CSMT; hCS-1; hCS-A; Choriomammotropin; PL

uniprot entry name :

CSH1_HUMAN

reactivity :

Mouse

specificity :

This assay has high sensitivity and excellent specificity for detection of PL. No significant cross-reactivity or interference between PL and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection between PL and all the analogues, therefore, cross reaction may still exist in some cases.

storage stability :

Store all reagents at 2-8 degree C.

other info1 :

Assay Type: Competitive or Sandwich. Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Sensitivity: 1.0 mug/L.

other info2 :

Intended Uses: This PL ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Mouse PL. This ELISA kit for research use only, not for therapeutic or diagnostic applications!

products description :

Principle of the assay: PL ELISA kit applies the quantitative sandwich enzyme immunoassay technique. The microtiter plate has been pre-coated with a monoclonal antibody specific for PL. Standards or samples are then added to the microtiter plate wells and PL if present, will bind to the antibody pre-coated wells. In order to quantitatively determine the amount of PL present in the sample, a standardized preparation of horseradish peroxidase (HRP)-conjugated polyclonal antibody, specific for PL are added to each well to "sandwich" the PL immobilized on the plate. The microtiter plate undergoes incubation, and then the wells are thoroughly washed to remove all unbound components. Next, substrate solutions are added to each well. The enzyme (HRP) and substrate are allowed to react over a short incubation period. Only those wells that contain PL and enzyme-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The PL concentration in each sample is interpolated from this standard curve.

ncbi gi num :

190034

ncbi acc num :

AAA98621.1

ncbi mol weight :

25,020 Da

ncbi pathways :

Cytokine Signaling In Immune System Pathway (366171); Growth Hormone Receptor Signaling Pathway (477128); Immune System Pathway (106386); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Nuclear Signaling By ERBB4 Pathway (530744); PI3K-Akt Signaling Pathway (692234); PI3K-Akt Signaling Pathway (692979)

ncbi summary :

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq, Jul 2008]

uniprot summary :

CSH1: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. Belongs to the somatotropin/prolactin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 17q24.2. Cellular Component: extracellular region. Molecular Function: hormone activity; metal ion binding

size1 :

48-Strip-Wells-(Competitive)

price1 :

470 USD

size2 :

48-Strip-Wells-(Sandwich)

price2 :

470

size3 :

96-Strip-Wells-(Competitive)

price3 :

675

size4 :

96-Strip-Wells-(Sandwich)

price4 :

675

more info or order :

MyBioSource product webpage