ELISA/assay

Rat Activating Transcription Factor 3 ELISA Kit

MBS722565

48-Strip-Wells

470 USD

ELISA Kit

Rat Activating Transcription Factor 3 ELISA Kit

Activating Transcription Factor 3

ATF3, partial; Cyclic AMP-dependent transcription factor ATF-3; cyclic AMP-dependent transcription factor ATF-3; cAMP-dependent transcription factor ATF-3; activating transcription factor 3; Activating transcription factor 3

ATF3

ATF3; ATF3; cAMP-dependent transcription factor ATF-3

ATF3_HUMAN

Rat

Store all reagents at 2-8 degree C.

Assay Type: Competitive

Highest Standards: 10ng/mL. Concentration of Standards: Concentration of Standards: 0,0.5,1.0,2.5,5.0,10ng/mL

Epigenetics and Nuclear Signaling

47496615

CAG29330.1

Q6ICQ9

14,314 Da

ATF-2 Transcription Factor Network Pathway (138006); ATF4 Activates Genes Pathway (530772); Direct P53 Effectors Pathway (137939); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889); Hypertrophy Model Pathway (198828); Id Signaling Pathway (198871); Metabolism Of Proteins Pathway (106230); Myometrial Relaxation And Contraction Pathways (198759); PERK Regulates Gene Expression Pathway (105907)

This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes. [provided by RefSeq, Apr 2011]

ATF-3: This protein binds the cAMP response element (CRE) (consensus: 5 -GTGACGT[AC][AG]-3 ), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters. Belongs to the bZIP family. ATF subfamily. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription factor. Chromosomal Location of Human Ortholog: 1q32.3. Cellular Component: nucleoplasm; nucleolus; nucleus. Molecular Function: identical protein binding; protein binding; protein homodimerization activity; protein heterodimerization activity; transcription corepressor activity; transcription factor activity. Biological Process: cellular protein metabolic process; unfolded protein response, activation of signaling protein activity; transcription, DNA-dependent; unfolded protein response; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; gluconeogenesis

48-Strip-Wells

470 USD

96-Strip-Wells

675