catalog number :
MBS7224648
products type :
ELISA Kit
products full name :
Human beta 1, 3 galactosyl O glycosyl glycoprotein beta 1, 6 N acetylglucosaminyltransferase 3 (GCNT3) ELISA Kit
products short name :
beta 1, 3 galactosyl O glycosyl glycoprotein beta 1, 6 N acetylglucosaminyltransferase 3 (GCNT3)
products name syn :
Human b 1, 3 galactosyl O glycosyl glycoprotein b 1, 6 N acetylglucosaminyltransferase 3 (GCNT3) ELISA Kit
other names :
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3; hC2GnT-M; C2GnT-mucin type; beta1,6GlcNAc-transferase; beta1,6-N-acetylglucosaminyltransferase-M; core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase; mucus-type core 2 beta-1,6-N-acetylglucosaminyltransferase; glucosaminyl (N-acetyl) transferase 3, mucin type; C2GnT-mucin type; C2GnT-M; hC2GnT-M; Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase; C2/4GnT
other gene names :
GCNT3; GCNT3; GNTM; C24GNT; C2GNT2; C2GNTM; C2/4GnT; C2GnT-M; hC2GnT-M; C2/4GnT
uniprot entry name :
GCNT3_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
products categories :
Cell Biology
ncbi mol weight :
50,864 Da
ncbi pathways :
Metabolic Pathways (132956); Metabolism Of Proteins Pathway (106230); Mucin Type O-Glycan Biosynthesis Pathway (82977); Mucin Type O-Glycan Biosynthesis Pathway (347); O-glycan Biosynthesis, Mucin Type Core Pathway (413362); O-glycan Biosynthesis, Mucin Type Core Pathway (468249); O-linked Glycosylation Pathway (980459); O-linked Glycosylation Of Mucins Pathway (530747); Post-translational Protein Modification Pathway (161012)
ncbi summary :
This gene encodes a member of the N-acetylglucosaminyltransferase family. The encoded protein is a beta-6-N-acetylglucosamine-transferase that catalyzes the formation of core 2 and core 4 O-glycans on mucin-type glycoproteins.[provided by RefSeq, Apr 2009]
uniprot summary :
GCNT3: Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. Belongs to the glycosyltransferase 14 family. Protein type: EC 2.4.1.102; EC 2.4.1.150; Glycan Metabolism - O-glycan biosynthesis; Transferase; Membrane protein, integral. Chromosomal Location of Human Ortholog: 15q21.3. Cellular Component: Golgi membrane; membrane; integral to membrane. Molecular Function: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity; N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity; acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity. Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; tissue morphogenesis; O-glycan processing; immunoglobulin production in mucosal tissue; carbohydrate metabolic process; post-translational protein modification; intestinal absorption