catalog number :
MBS7223613
products type :
ELISA Kit
products full name :
Rat Centrin-2 (CETN2) ELISA Kit
products short name :
Centrin-2 (CETN2)
other names :
centrin-2; Centrin-2; centrin-2; caltractin (20kD calcium-binding protein); centrin, EF-hand protein, 2; Caltractin isoform 1
products gene name :
CETN2
other gene names :
CETN2; CETN2; CALT; CEN2; CALT; CEN2
uniprot entry name :
CETN2_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
products categories :
Signal Transduction
ncbi acc num :
NP_004335.1
ncbi gb acc num :
NM_004344.1
ncbi mol weight :
19,738 Da
ncbi pathways :
Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); Centrosome Maturation Pathway (105807); G2/M Transition Pathway (105801); Loss Of Nlp From Mitotic Centrosomes Pathway (105811); Loss Of Proteins Required For Interphase Microtubule Organization From The Centrosome Pathway (105810); Mitotic G2-G2/M Phases Pathway (160942); Nucleotide Excision Repair Pathway (83044); Nucleotide Excision Repair Pathway (452); Recruitment Of Mitotic Centrosome Proteins And Complexes Pathway (105808)
ncbi summary :
Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. [provided by RefSeq, Jul 2008]
uniprot summary :
CETN2: a calcium-binding proteins and is a structural component of the centrosome. Contains 4 EF-hand calcium-binding domains. Highly conserved from algae to humans. Its association with the centrosome suggests that it plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. Protein type: DNA repair, damage; Cell cycle regulation; Calcium-binding. Chromosomal Location of Human Ortholog: Xq28. Cellular Component: centriole; centrosome; intracellular; cytosol; photoreceptor connecting cilium. Molecular Function: protein binding; microtubule binding; G-protein beta/gamma-subunit binding; calcium ion binding; heterotrimeric G-protein binding. Biological Process: mitosis; cell division; nucleotide-excision repair; organelle organization and biogenesis; spermatogenesis; centriole replication; mitotic cell cycle; G2/M transition of mitotic cell cycle; regulation of cytokinesis