product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse Podocin ELISA Kit
catalog :
MBS722280
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
citations: 1
Reference
Gu S, Yeh T, Lin S, Peng F. Unfractionated bone marrow cells attenuate paraquat-induced glomerular injury and acute renal failure by modulating the inflammatory response. Sci Rep. 2016;6:23287 pubmed publisher
product information
catalog number :
MBS722280
products type :
ELISA Kit
products full name :
Mouse Podocin ELISA Kit
products short name :
Podocin
other names :
podocin isoform 1; Podocin; podocin; nephrosis 2, idiopathic, steroid-resistant (podocin)
products gene name :
PDCN
other gene names :
NPHS2; NPHS2; PDCN; SRN1
uniprot entry name :
PODO_HUMAN
reactivity :
Mouse
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Assay Type: Competitive
other info2 :
Highest Standards: 25ng/mL. Concentration of Standards: Concentration of Standards: 0,1.0,2.5,5.0,10,25ng/mL
ncbi gi num :
7657615
ncbi acc num :
NP_055440.1
ncbi gb acc num :
NM_014625.3
ncbi mol weight :
34,421 Da
ncbi pathways :
Nephrin/Neph1 Signaling In The Kidney Podocyte Pathway (138072)
ncbi summary :
This gene encodes a protein that plays a role in the regulation of glomerular permeability. Mutations in this gene cause steroid-resistant nephrotic syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
uniprot summary :
NPHS2: Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton. Defects in NPHS2 are the cause of nephrotic syndrome type 2 (NPHS2). It is a renal disorder characterized clinically by childhood onset of proteinuria, hypoalbuminemia, hyperlipidemia, and edema. Kidney biopsies show non-specific histologic changes such as focal segmental glomerulosclerosis and diffuse mesangial proliferation. The disorder is resistant to steroid treatment and progresses to end-stage renal failure in the first or second decades. Some patients show later onset of the disorder. Belongs to the band 7/mec-2 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 1q25.2. Cellular Component: protein complex; endoplasmic reticulum; integral to plasma membrane; plasma membrane; intercellular junction; lipid raft. Molecular Function: protein binding. Biological Process: actin cytoskeleton reorganization; excretion. Disease: Nephrotic Syndrome, Type 2
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
675
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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