ELISA/assay

Rat A Disintegrin And Metalloproteinase With Thrombospondin 1 ELISA Kit

MBS722015

48-Strip-Wells-(Comp

470 USD

ELISA Kit

Rat A Disintegrin And Metalloproteinase With Thrombospondin 1 ELISA Kit

A Disintegrin And Metalloproteinase With Thrombospondin 1

A disintegrin and metalloproteinase with thrombospondin motifs 1 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 1; A disintegrin and metalloproteinase with thrombospondin motifs 1; METH-1; ADAM-TS1; ADAMTS-1; ADAM-TS 1; human metalloproteinase with thrombospondin type 1 motifs; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; ADAM metallopeptidase with thrombospondin type 1 motif, 1; METH-1

ADAMTS1

ADAMTS1; ADAMTS1; C3-C5; METH1; KIAA1346; METH1; ADAM-TS 1; ADAM-TS1; ADAMTS-1

ATS1_HUMAN

Rat

Store all reagents at 2-8 degree C.

Assay Type: Competitive or Sandwich

Highest Standards: 5000pg/mL. Concentration of Standards: Concentration of Standards: 0,250,500,1000,2500,5000pg/mL

Cardiovascular

50845384

NP_008919.3

NM_006988.3

105,358 Da

Degradation Of The Extracellular Matrix Pathway (576263); Endochondral Ossification Pathway (198812); Extracellular Matrix Organization Pathway (576262); Metabolism Of Proteins Pathway (106230); O-glycosylation Of TSR Domain-containing Proteins Pathway (980460); O-linked Glycosylation Pathway (980459); Post-translational Protein Modification Pathway (161012)

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function. [provided by RefSeq, Jul 2008]

ADAMTS1: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture. Protein type: Motility/polarity/chemotaxis; Secreted; Protease; Secreted, signal peptide; EC 3.4.24.-. Chromosomal Location of Human Ortholog: 21q21.2. Cellular Component: cytoplasm; basement membrane; cytoplasmic vesicle. Molecular Function: heparin binding; zinc ion binding; metallopeptidase activity; metalloendopeptidase activity. Biological Process: integrin-mediated signaling pathway; negative regulation of cell proliferation; kidney development; ovulation from ovarian follicle; proteolysis

48-Strip-Wells-(Competitive)

470 USD

48-Strip-Wells-(Sandwich)

470

96-Strip-Wells-(Competitive)

675

96-Strip-Wells-(Sandwich)

675