product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Bifunctional protein NCOAT (MGEA5) ELISA Kit
catalog :
MBS7213506
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS7213506
products type :
ELISA Kit
products full name :
Human Bifunctional protein NCOAT (MGEA5) ELISA Kit
products short name :
Bifunctional protein NCOAT (MGEA5)
other names :
bifunctional protein NCOAT isoform b; Bifunctional protein NCOAT; bifunctional protein NCOAT; O-GlcNAcase; hyaluronidase in meningioma; meningioma-expressed antigen 5; nuclear cytoplasmic O-GlcNAcase and acetyltransferase; meningioma expressed antigen 5 (hyaluronidase); Meningioma-expressed antigen 5; Nuclear cytoplasmic O-GlcNAcase and acetyltransferaseIncluding the following 2 domains:Protein O-GlcNAcase (EC:3.2.1.169)Alternative name(s):Glycoside hydrolase O-GlcNAcase; Hexosaminidase C; N-acetyl-beta-D-glucosaminidase; N-acetyl-beta-glucosaminidase; O-GlcNAcase; OGA
products gene name :
MGEA5
other gene names :
MGEA5; MGEA5; OGA; MEA5; NCOAT; HEXC; KIAA0679; MEA5; OGA; HAT
uniprot entry name :
NCOAT_HUMAN
reactivity :
Human
storage stability :
Store all reagents at 2-8 degree C.
ncbi gi num :
215490056
ncbi acc num :
NP_001135906.1
ncbi gb acc num :
NM_001142434.1
ncbi mol weight :
96,932 Da
ncbi pathways :
Protein O-[N-acetyl]-glucosylation Pathway (982231)
ncbi summary :
The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008]
uniprot summary :
OGA: Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl- beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity. Acetylates Lys-8 of histone H4 and Lys-14 of histone H3. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Acetyltransferase; Hydrolase; EC 3.2.1.169; EC 3.2.1.52. Chromosomal Location of Human Ortholog: 10q24.1-q24.3. Cellular Component: membrane; cytosol; nucleus. Molecular Function: beta-N-acetylglucosaminidase activity; histone acetyltransferase activity; hyalurononglucosaminidase activity. Biological Process: positive regulation of DNA metabolic process; positive regulation of protein complex disassembly; dATP metabolic process; positive regulation of proteolysis; protein deglycosylation; N-acetylglucosamine metabolic process; positive regulation of insulin secretion; positive regulation of growth hormone secretion; positive regulation of glucose import; negative regulation of protein amino acid glycosylation; positive regulation of mitochondrial depolarization; response to steroid hormone stimulus; positive regulation of cell killing; glycoprotein catabolic process; histone acetylation; protein targeting to membrane; aging
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
675
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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