catalog number :
MBS7211618
products type :
ELISA Kit
products full name :
Mouse CD2-associated protein (CD2AP) ELISA Kit
products short name :
CD2-associated protein (CD2AP)
other names :
CD2-associated protein; CD2-associated protein; CD2-associated protein; adapter protein CMS; cas ligand with multiple SH3 domains; Cas ligand with multiple Src homology 3 (SH3) domains; CD2-associated protein; Adapter protein CMS; Cas ligand with multiple SH3 domains
products gene name :
CD2AP
other gene names :
CD2AP; CD2AP; CMS
uniprot entry name :
CD2AP_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
products categories :
Immunology
ncbi acc num :
NP_036252.1
ncbi gb acc num :
NM_012120.2
ncbi mol weight :
71,451 Da
ncbi pathways :
Bacterial Invasion Of Epithelial Cells Pathway 149807!!Bacterial Invasion Of Epithelial Cells Pathway 148661!!Cell-Cell Communication Pathway 477132!!Nephrin Interactions Pathway 187228!!Nephrin/Neph1 Signaling In The Kidney Podocyte Pathway 138072!!VEGFR1 Specific Signals Pathway 137924
ncbi summary :
This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq, Jul 2008]