product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Guinea pig Paxillin ELISA Kit
catalog :
MBS721124
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS721124
products type :
ELISA Kit
products full name :
Guinea pig Paxillin ELISA Kit
products short name :
Paxillin
other names :
paxillin; Paxillin; paxillin; myocardial ischemic preconditioning associated protein 7; paxillin
products gene name :
Pax
other gene names :
Pxn; Pxn
uniprot entry name :
PAXI_RAT
reactivity :
Guinea Pig
storage stability :
Store all reagents at 2-8 degree C.
ncbi gi num :
58865866
ncbi acc num :
NP_001012147.1
ncbi gb acc num :
NM_001012147.1
ncbi mol weight :
64,019 Da
ncbi pathways :
Androgen Receptor Signaling Pathway (198529); Bacterial Invasion Of Epithelial Cells Pathway (149774); Bacterial Invasion Of Epithelial Cells Pathway (148661); Cell Junction Organization Pathway (1010358); Cell-Cell Communication Pathway (1010357); Cell-extracellular Matrix Interactions Pathway (1010363); Chemokine Signaling Pathway (98755); Chemokine Signaling Pathway (96864); Disease Pathway (1010484); EGFR1 Signaling Pathway (198427)
uniprot summary :
PXN: a multi-domain cytoskeletal protein involved in actin-membrane attachment that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions. Binds in vitro to vinculin as well as to the SH3 domain of c-SRC and, when tyrosine phosphorylated, to the Crk SH2 domain. Interacts with GIT1, NUDT16L1/SDOS, PARVA and TGFB1I1. Component of cytoplasmic complexes, which also contain GIT1, ARHGEF6 and PAK1. Binds DDEF2. Interacts with unphosphorylated ITGA4. Interacts with RNF5.Three alternatively-spliced isoforms have been described. Isoform beta binds to focal adhesion kinase but weakly to vinculin. Isoform gamma binds to vinculin but only weakly to focal adhesion kinase. Protein type: Cell adhesion; Adaptor/scaffold; Motility/polarity/chemotaxis; Cytoskeletal. Cellular Component: nucleoplasm; cytoskeleton; focal adhesion; lamellipodium; cytoplasm; leading edge; plasma membrane; stress fiber; cell cortex; nucleus. Molecular Function: integrin binding; zinc ion binding; beta-catenin binding; protein complex binding; BH4 domain binding; protein kinase binding; vinculin binding. Biological Process: focal adhesion formation; integrin-mediated signaling pathway; lamellipodium biogenesis; regulation of cell shape; peptidyl-tyrosine phosphorylation; branching morphogenesis of a tube; activation of MAPK activity; cell-matrix adhesion; positive regulation of protein kinase activity; transforming growth factor beta receptor signaling pathway; cytoskeleton organization and biogenesis
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
675
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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