product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse Thromboxane A2 ELISA Kit
catalog :
MBS720990
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS720990
products type :
ELISA Kit
products full name :
Mouse Thromboxane A2 ELISA Kit
products short name :
Thromboxane A2
other names :
thromboxane A2 receptor isoform beta; Thromboxane A2 receptor; thromboxane A2 receptor; prostanoid TP receptor; thromboxane A2 receptor; Prostanoid TP receptor
products gene name :
TX-A2
other gene names :
TBXA2R; TBXA2R; TXA2-R; BDPLT13; TXA2-R
uniprot entry name :
TA2R_HUMAN
reactivity :
Mouse
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Assay Type: Competitive
other info2 :
Highest Standards: 1000pg/mL. Concentration of Standards: Concentration of Standards: 0,50,100,250,500,1000pg/mL
products categories :
Cardiovascular
ncbi gi num :
260593681
ncbi acc num :
NP_963998.2
ncbi gb acc num :
NM_201636.2
ncbi mol weight :
44,205 Da
ncbi pathways :
Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Eicosanoid Ligand-binding Receptors Pathway (106370); G Alpha (12/13) Signalling Events Pathway (106041); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295)
ncbi summary :
This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
uniprot summary :
TXA2-R: Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase. Defects in TBXA2R are the cause of susceptibility to bleeding disorder platelet-type 13 (BDPLT13). BDPLT13 is a disorder characterized by reduced platelet aggregation and a tendency to mild mucocutaneous bleeding. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: integral to plasma membrane; acrosome; plasma membrane. Molecular Function: protein binding; guanyl-nucleotide exchange factor activity; thromboxane A2 receptor activity. Biological Process: second-messenger-mediated signaling; response to drug; G-protein coupled receptor protein signaling pathway; platelet activation; elevation of cytosolic calcium ion concentration; positive regulation of angiogenesis; positive regulation of vasoconstriction; response to lipopolysaccharide; positive regulation of smooth muscle contraction; blood coagulation; inflammatory response; positive regulation of blood pressure; response to nutrient; positive regulation of GTPase activity
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
675
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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