catalog number :
MBS720612
products type :
ELISA Kit
products full name :
Human Anti Apolipoprotein Antibodies ELISA Kit
products short name :
Anti Apolipoprotein Antibodies
other names :
apolipoprotein B-100; Apolipoprotein B-100; apolipoprotein B-100; apoB-48; apoB-100; apo B-100; mutant Apo B 100; apolipoprotein B48; apolipoprotein B (including Ag(x) antigen); apolipoprotein B
products gene name :
AAHA
other gene names :
APOB; APOB; FLDB; LDLCQ4; Apo B-100; Apo B-48
uniprot entry name :
APOB_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
other info2 :
ELISA Method: Sandwich. Highest Standards: 100U/L. Concentration of Standards: Concentration of Standards: 0,5,10,25,50,100U/L
products categories :
Cardiovascular
ncbi acc num :
NP_000375.2
ncbi gb acc num :
NM_000384.2
ncbi mol weight :
515,605 Da
ncbi pathways :
Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!Cell Surface Interactions At The Vascular Wall Pathway 106062!!Chylomicron-mediated Lipid Transport Pathway 106157!!Disease Pathway 530764!!Diseases Associated With Visual Transduction Pathway 771581!!FOXA1 Transcription Factor Network Pathway 137979!!Fat Digestion And Absorption Pathway 194385!!Fat Digestion And Absorption Pathway 194324!!Hemostasis Pathway 106028!!LDL-mediated Lipid Transport Pathway 106159
ncbi summary :
This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA- UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]