catalog number :
MBS7204775
products type :
ELISA Kit
products full name :
Human 1 acyl sn glycerol 3 phosphate acyltransferase Alpha (AGPAT1) ELISA Kit
products short name :
1 acyl sn glycerol 3 phosphate acyltransferase Alpha (AGPAT1)
other names :
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; 1-AGPAT 1; 1-AGP acyltransferase 1; lysophospholipid acyltransferase; lysophosphatidic acid acyltransferase alpha; 1-acylglycerol-3-phosphate O-acyltransferase 1 (acetoacetly Coenzyme A thiolase); 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha); 1-acylglycerol-3-phosphate O-acyltransferase 1; 1-acylglycerol-3-phosphate O-acyltransferase 1; 1-AGP acyltransferase 1; 1-AGPAT 1; Lysophosphatidic acid acyltransferase alpha; LPAAT-alpha; Protein G15
products gene name :
AGPAT1
other gene names :
AGPAT1; AGPAT1; G15; LPAATA; 1-AGPAT1; LPAAT-alpha; G15; 1-AGP acyltransferase 1; 1-AGPAT 1; LPAAT-alpha
uniprot entry name :
PLCA_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
ncbi mol weight :
31,717 Da
ncbi pathways :
CDP-diacylglycerol Biosynthesis I Pathway (142255); CDP-diacylglycerol Biosynthesis I Pathway (138606); ChREBP Activates Metabolic Gene Expression Pathway (106104); Fat Digestion And Absorption Pathway (194385); Fat Digestion And Absorption Pathway (194324); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Glycerolipid Metabolism Pathway (82986); Glycerolipid Metabolism Pathway (361); Glycerophospholipid Biosynthesis Pathway (645313); Glycerophospholipid Metabolism Pathway (82989)
ncbi summary :
This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
uniprot summary :
AGPAT1: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. Protein type: EC 2.3.1.51; Lipid Metabolism - ether lipid; Membrane protein, multi-pass; Membrane protein, integral; Lipid Metabolism - glycerolipid; Lipid Metabolism - glycerophospholipid; Transferase. Chromosomal Location of Human Ortholog: 6p21.3. Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane. Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity. Biological Process: positive regulation of cytokine production; phospholipid metabolic process; glycerophospholipid biosynthetic process; positive regulation of cellular metabolic process; energy reserve metabolic process; phosphatidic acid biosynthetic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; CDP-diacylglycerol biosynthetic process; positive regulation of cytokine and chemokine mediated signaling pathway