catalog number :
MBS719993
products full name :
Rabbit anti-human Ferritin light chain polyclonal Antibody
products short name :
Ferritin light chain
products name syn :
FTL; Ferritin L subunit
other names :
ferritin light chain; Ferritin light chain; ferritin light chain; ferritin L-chain; ferritin L subunit; ferritin light polypeptide-like 3; ferritin, light polypeptide
other gene names :
FTL; FTL; LFTD; NBIA3; Ferritin L subunit
uniprot entry name :
FRIL_HUMAN
purity :
Caprylic Acid Ammonium Sulfate Precipitation Purified
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
Western Blot (WB), ELISA (EIA)
other info1 :
Immunogen: Recombinant human Ferritin light chain protein. Relevance: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
other info2 :
Storage Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
. Conjugate: Non-conjugated
ncbi acc num :
NP_000137.2
ncbi gb acc num :
NM_000146.3
ncbi mol weight :
20,020 Da
ncbi pathways :
Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!Clathrin Derived Vesicle Budding Pathway 119545!!Golgi Associated Vesicle Biogenesis Pathway 119546!!Integrated Pancreatic Cancer Pathway 711360!!Iron Uptake And Transport Pathway 187191!!Membrane Trafficking Pathway 106160!!Mineral Absorption Pathway 212237!!Mineral Absorption Pathway 212220!!Scavenging By Class A Receptors Pathway 833814!!Transmembrane Transport Of Small Molecules Pathway 106572
ncbi summary :
This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]