Rabbit anti-human Actin, cytoplasmic 1 polyclonal Antibody, Biotin conjugated | MyBioSource MBS719819 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit anti-human Actin, cytoplasmic 1 polyclonal Antibody, Biotin conjugated

catalog :

MBS719819

quantity :

0.05 mg

price :

160 USD

clonality :

polyclonal

host :

rabbit

conjugate :

biotin

reactivity :

human

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS719819

products type :

Antibody

products full name :

Rabbit anti-human Actin, cytoplasmic 1 polyclonal Antibody, Biotin conjugated

products short name :

Actin, cytoplasmic 1

products name syn :

Beta-actin; ACTB

other names :

actin, cytoplasmic 1; Actin, cytoplasmic 1; actin, cytoplasmic 1; actin, beta; Beta-actin

other gene names :

ACTB; ACTB; BRWS1; PS1TP5BP1

uniprot entry name :

ACTB_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

sequence length :

375

purity :

Caprylic Acid Ammonium Sulfate Precipitation Purified

storage stability :

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

tested application :

Western Blot (WB), ELISA (EIA). Not yet tested in other applications.

other info1 :

Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: Biotin

other info2 :

Immunogen: Recombinant human Actin, cytoplasmic 1 protein

products description :

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

ncbi gi num :

4501885

ncbi acc num :

NP_001092.1

ncbi gb acc num :

NM_001101.3

uniprot acc num :

P60709

ncbi mol weight :

41,737 Da

ncbi pathways :

Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Arrhythmogenic Right Ventricular Cardiomyopathy Pathway (672454); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (117293); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (116129); Axon Guidance Pathway (1270303); B-WICH Complex Positively Regulates RRNA Expression Pathway (1339126); Bacterial Invasion Of Epithelial Cells Pathway (149807); Bacterial Invasion Of Epithelial Cells Pathway (148661); Chaperonin-mediated Protein Folding Pathway (1268694)

ncbi summary :

This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008]

uniprot summary :

ACTB: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57 SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. Found in a complex with XPO6, Ran, ACTB and PFN1. Component of the MLL5-L complex, at least composed of MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT. Interacts with XPO6 and EMD. Interacts with ERBB2. Interacts with GCET2. Belongs to the actin family. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 7p22. Cellular Component: cytoplasm; cytoskeleton; cytosol; extracellular space; focal adhesion; membrane; NuA4 histone acetyltransferase complex; nuclear chromatin; nucleoplasm; plasma membrane; protein complex; ribonucleoprotein complex. Molecular Function: ATP binding; identical protein binding; kinesin binding; nitric-oxide synthase binding; nucleosomal DNA binding; protein binding; structural constituent of cytoskeleton; Tat protein binding. Biological Process: 'de novo' posttranslational protein folding; ATP-dependent chromatin remodeling; axon guidance; blood coagulation; cell motility; cellular protein metabolic process; ephrin receptor signaling pathway; establishment and/or maintenance of chromatin architecture; gene expression; innate immune response; intercellular junction assembly and maintenance; positive regulation of gene expression, epigenetic; protein folding; regulation of gene expression, epigenetic; retinal homeostasis; small GTPase mediated signal transduction; substantia nigra development; vascular endothelial growth factor receptor signaling pathway. Disease: Baraitser-winter Syndrome 1; Dystonia, Juvenile-onset

size1 :

0.05 mg

price1 :

160 USD

size2 :

0.1 mg

price2 :

235

more info or order :

MyBioSource product webpage