catalog number :
MBS719667
products full name :
Rabbit anti-human Ferritin heavy chain polyclonal Antibody, FITC
products short name :
[Ferritin heavy chain]
products name syn :
[Ferritin heavy chain (Ferritin H subunit) (EC 1.16.3.1) (Cell proliferation-inducinggene 15 protein) [Cleaved into: Ferritin heavy chain, N-terminally processed],FTH1, FTH FTHL6]
other names :
[ferritin heavy chain; Ferritin heavy chain; ferritin heavy chain; ferritin, heavy polypeptide 1; Cell proliferation-inducing gene 15 protein]
other gene names :
[FTH1; FTH1; FHC; FTH; HFE5; PLIF; FTHL6; PIG15; FTH; FTHL6; Ferritin H subunit]
uniprot entry name :
FRIH_HUMAN
purity :
>95%, Protein G purified
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA)
other info1 :
Immunogen: Recombinant Human Ferritin heavy chain protein (2-183AA). Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: FITC. Species: Human. Research Area: Neuroscience
other info2 :
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-14416 / sc-25617
ncbi acc num :
NP_002023.2
ncbi gb acc num :
NM_002032.2
ncbi pathways :
Binding And Uptake Of Ligands By Scavenger Receptors Pathway (1269897); Clathrin Derived Vesicle Budding Pathway (1269881); Golgi Associated Vesicle Biogenesis Pathway (1269882); Iron Metabolism In Placenta Pathway (672461); Iron Uptake And Transport Pathway (1269948); Membrane Trafficking Pathway (1269877); Mineral Absorption Pathway (212237); Mineral Absorption Pathway (212220); Scavenging By Class A Receptors Pathway (1269899); Transmembrane Transport Of Small Molecules Pathway (1269903)
ncbi summary :
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
uniprot summary :
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney ().