product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) polyclonal Antibody
catalog :
MBS719289
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
BMP
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS719289
products type :
Antibody
products full name :
Rabbit anti-human BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) polyclonal Antibody
products short name :
BMP and activin membrane-bound inhibitor homolog
other names :
BMP and activin membrane-bound inhibitor homolog; BMP and activin membrane-bound inhibitor homolog; BMP and activin membrane-bound inhibitor homolog; non-metastatic gene A protein; putative transmembrane protein NMA; BMP and activin membrane-bound inhibitor; Non-metastatic gene A protein; Putative transmembrane protein NMA
other gene names :
BAMBI; BAMBI; NMA; NMA
uniprot entry name :
BAMBI_HUMAN
clonality :
Polyclonal
isotype :
IgG
reactivity :
Human, Mouse, Rat
sequence length :
260
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human BAMBI
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
6912534
ncbi acc num :
NP_036474.1
ncbi gb acc num :
NM_012342.2
ncbi mol weight :
29,108 Da
ncbi pathways :
BMP Receptor Signaling Pathway (137948); Disease Pathway (530764); Downregulation Of TGF-beta Receptor Signaling Pathway (645293); Loss Of Function Of SMAD2/3 In Cancer Pathway (906019); Loss Of Function Of SMAD4 In Cancer Pathway (906017); Loss Of Function Of TGFBR1 In Cancer Pathway (906025); Loss Of Function Of TGFBR2 In Cancer Pathway (906022); SMAD2/3 MH2 Domain Mutants In Cancer Pathway (906021); SMAD2/3 Phosphorylation Motif Mutants In Cancer Pathway (906020); SMAD4 MH2 Domain Mutants In Cancer Pathway (906018)
ncbi summary :
This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008]
uniprot summary :
BAMBI: Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. Protein type: Membrane protein, integral; Inhibitor. Chromosomal Location of Human Ortholog: 10p12.3-p11.2. Cellular Component: cytoplasm; integral to membrane; plasma membrane. Molecular Function: frizzled binding; punt binding. Biological Process: regulation of cell shape; cell migration; positive regulation of protein binding; transforming growth factor beta receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of cell proliferation; negative regulation of transforming growth factor beta receptor signaling pathway
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

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