product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human UDP-glucose ceramide glucosyltransferase polyclonal Antibody
catalog :
MBS719269
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
ELISA
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS719269
products type :
Antibody
products full name :
Rabbit anti-human UDP-glucose ceramide glucosyltransferase polyclonal Antibody
products short name :
UDP-glucose ceramide glucosyltransferase
products name syn :
UDP-glucose ceramide glucosyltransferase; UGCG; GCS
other names :
UDP-glucose ceramide glucosyltransferase; Ceramide glucosyltransferase; ceramide glucosyltransferase; GLCT-1; glucosylceramide synthase; UDP-glucose:N-acylsphingosine D-glucosyltransferase; UDP-glucose ceramide glucosyltransferase; GLCT-1; Glucosylceramide synthase; GCS; UDP-glucose ceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferase
other gene names :
UGCG; UGCG; GCS; GLCT1; GCS
uniprot entry name :
CEGT_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human,mouse,rat?Other species are not tested. Please decide the specificity by homology.
sequence length :
394
purity :
Antigen Affinity Purified
form :
Liquid
storage stability :
Shipped at 4 Degree C. Upon delivery aliquot and store at -20 Degree C or -80 Degree C. Avoid repeated freeze.
tested application :
ELISA: Use at an assay dependent dilution. WB: 1:500-1:5000 . IP: 1:200-1:2000. IHC: 1:50-1:200 (Recommender dilutions) . Positive WB detected in: A375 cells, mouse brain tissue . Positive IP detected in: A375 cells . Positive IHC detect
other info1 :
Immunogen: Human UGCG. Conjugate : Non-conjugated
other info2 :
Storage Buffer: PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
products description :
Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase".
ncbi gi num :
24270822
ncbi acc num :
AAH38711.1
ncbi mol weight :
44,854 Da
ncbi pathways :
Glycosphingolipid Metabolism Pathway (530751); IL2 Signaling Events Mediated By PI3K Pathway (137938); Lactosylceramide Biosynthesis Pathway (413367); Lactosylceramide Biosynthesis Pathway (468259); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Sphingolipid Metabolism Pathway (82994); Sphingolipid Metabolism Pathway (119543); Sphingolipid Metabolism Pathway (369)
ncbi summary :
Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation. [provided by RefSeq, Oct 2009]
uniprot summary :
UGCG: Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a flippase. Belongs to the glycosyltransferase 2 family. Protein type: Lipid Metabolism - sphingolipid; Transferase; Membrane protein, multi-pass; Membrane protein, integral; EC 2.4.1.80. Chromosomal Location of Human Ortholog: 9q31. Cellular Component: Golgi membrane; membrane; integral to membrane. Molecular Function: ceramide glucosyltransferase activity. Biological Process: epidermis development; sphingolipid metabolic process; glycosphingolipid biosynthetic process; glycosphingolipid metabolic process; glucosylceramide biosynthetic process
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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