catalog number :
MBS719156
products full name :
Rabbit anti-human karyopherin alpha 1 (importin alpha 5) polyclonal Antibody
products short name :
karyopherin alpha 1 (importin alpha 5)
products name syn :
karyopherin alpha 1 (importin alpha 5); KPNA1; IPOA5; NPI-1; RCH2; SRP1
other names :
Karyopherin alpha 1 (importin alpha 5); Importin subunit alpha-5; importin subunit alpha-5; SRP1-beta; importin alpha 5; importin-alpha-S1; RAG cohort protein 2; importin subunit alpha-1; nucleoprotein interactor 1; karyopherin subunit alpha-1; recombination activating gene cohort 2; karyopherin alpha 1 (importin alpha 5); Karyopherin subunit alpha-1; Nucleoprotein interactor 1; NPI-1; RAG cohort protein 2; SRP1-betaCleaved into the following chain:Importin subunit alpha-5, N-terminally processed
other gene names :
KPNA1; KPNA1; RCH2; SRP1; IPOA5; NPI-1; RCH2; NPI-1
uniprot entry name :
IMA5_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
other info1 :
Immunogen: Human KPNA1
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAH90864.1
ncbi mol weight :
60,222 Da
ncbi pathways :
Activation Of DNA Fragmentation Factor Pathway 105683!!Antiviral Mechanism By IFN-stimulated Genes Pathway 530760!!Apoptosis Pathway 105648!!Apoptosis Induced DNA Fragmentation Pathway 105682!!Apoptotic Execution Phase Pathway 105677!!Class I PI3K Signaling Events Mediated By Akt Pathway 138020!!Cytokine Signaling In Immune System Pathway 366171!!Disease Pathway 530764!!HIV Infection Pathway 105983!!Host Interactions Of HIV Factors Pathway 106010
ncbi summary :
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]