catalog number :
MBS719154
products full name :
Rabbit anti-human lysyl oxidase polyclonal Antibody
products short name :
lysyl oxidase
products name syn :
lysyl oxidase; LOX; MGC105112
other names :
lysyl oxidase; Protein-lysine 6-oxidase; protein-lysine 6-oxidase; lysyl oxidase; Lysyl oxidase
other gene names :
LOX; LOX
uniprot entry name :
LYOX_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human LOX
other info2 :
Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAB23549.1
ncbi mol weight :
46,944 Da
ncbi pathways :
Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway 730306!!Collagen Formation Pathway 645288!!Crosslinking Of Collagen Fibrils Pathway 730308!!Elastic Fibre Formation Pathway 730310!!Extracellular Matrix Organization Pathway 576262
ncbi summary :
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]