catalog number :
MBS719083
products full name :
Rabbit anti-human microtubule-associated protein 2 polyclonal Antibody
products short name :
[microtubule-associated protein 2]
products name syn :
[microtubule-associated protein 2; MAP2; DKFZp686I2148; MAP2A; MAP2B; MAP2C]
other names :
[microtubule associated protein 2, partial; Microtubule-associated protein 2; microtubule-associated protein 2; MAP-2; microtubule-associated protein 2]
other gene names :
[MAP2; MAP2; MAP2A; MAP2B; MAP2C; MAP-2]
uniprot entry name :
MTAP2_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
form :
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
other info1 :
Immunogen: Human MAP2B. Product Type: Purified Rabbit Anti human PolyClonal Antibody. Species: Homo sapiens (Human)
other info2 :
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-5357 / sc-5359 / sc-12012 / sc-20172
products description :
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isforms have been described.
ncbi acc num :
AAA59552.1
ncbi pathways :
LKB1 Signaling Events Pathway (137957); MAPK Cascade Pathway (198834); SIDS Susceptibility Pathways (198901)
ncbi summary :
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]
uniprot summary :
MAP2: a member of the microtubule-associated protein (MAP) family. Its exact function is unknown but MAPs appear to stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. Expressed at high levels in neural tissue and the prostate. Four alternatively spliced transcript variants have been reported. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 2q34-q35. Cellular Component: microtubule; microtubule associated complex; cell soma; cytoplasm; nucleolus; dendritic shaft. Molecular Function: calmodulin binding; protein binding; microtubule binding; structural molecule activity. Biological Process: axonogenesis; dendrite morphogenesis; microtubule bundle formation; neurite development; central nervous system neuron development