catalog number :
MBS718923
products type :
Recombinant Protein
products full name :
Recombinant Human Sarcoplasmic reticulum histidine-rich calcium-binding protein (HRC)
products short name :
Sarcoplasmic reticulum histidine-rich calcium-binding protein (HRC)
products name syn :
Sarcoplasmic reticulum histidine-rich calcium-binding protein
other names :
sarcoplasmic reticulum histidine-rich calcium-binding protein; Sarcoplasmic reticulum histidine-rich calcium-binding protein; sarcoplasmic reticulum histidine-rich calcium-binding protein; histidine rich calcium binding protein
products gene name syn :
HRC; HCP
other gene names :
HRC; HRC; HCP
uniprot entry name :
SRCH_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
29-699
sequence :
QL RGDGLGFRNR NNSTGVAGLS EEASAELRHH LHSPRDHPDE NKDVSTENGH HFWSHPDREK EDEDVSKEYG HLLPGHRSQD HKVGDEGVSG EEVFAEHGGQ ARGHRGHGSE DTEDSAEHRH HLPSHRSHSH QDEDEDEVVS SEHHHHILRH GHRGHDGEDD EGEEEEEEEE EEEEASTEYG HQAHRHRGHG SEEDEDVSDG HHHHGPSHRH QGHEEDDDDD DDDDDDDDDD DVSIEYRHQA HRHQGHGIEE DEDVSDGHHH RDPSHRHRSH EEDDNDDDDV STEYGHQAHR HQDHRKEEVE AVSGEHHHHV PDHRHQGHRD EEEDEDVSTE RWHQGPQHVH HGLVDEEEEE EEITVQFGHY VASHQPRGHK SDEEDFQDEY KTEVPHHHHH RVPREEDEEV SAELGHQAPS HRQSHQDEET GHGQRGSIKE MSHHPPGHTV VKDRSHLRKD DSEEEKEKEE DPGSHEEDDE SSEQGEKGTH HGSRDQEDEE DEEEGHGLSL NQEEEEEEDK EEEEEEEDEE RREERAEVGA PLSPDHSEEE EEEEEGLEED EPRFTIIPNP LDRREEAGGA SSEEESGEDT GPQDAQEYGN YQPGSLCGYC SFCNRCTECE SCHCDEENMG EHCDQCQHCQ FCYLCPLVCE TVCAPGSYVD YFSSSLYQAL ADMLETPEP
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
ncbi acc num :
NP_002143.1
ncbi gb acc num :
NM_002152.2
ncbi mol weight :
80,244 Da
ncbi summary :
This gene encodes a luminal sarcoplasmic reticulum protein identified by its ability to bind low-density lipoprotein with high affinity. The protein interacts with the cytoplasmic domain of triadin, the main transmembrane protein of the junctional sarcoplasmic reticulum (SR) of skeletal muscle. The protein functions in the regulation of releasable calcium into the SR. [provided by RefSeq, Sep 2008]
uniprot summary :
HRC: May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle. Protein type: Calcium-binding. Chromosomal Location of Human Ortholog: 19q13.3. Cellular Component: sarcoplasmic reticulum membrane; sarcoplasmic reticulum lumen; Z disc. Molecular Function: protein binding; calcium ion binding; ATPase binding. Biological Process: cytosolic calcium ion homeostasis; muscle contraction; regulation of heart rate; regulation of peptidyl-serine phosphorylation; positive regulation of heart rate; positive regulation of heart contraction
size2 :
0.05 mg (Baculovirus)
size4 :
0.05 mg (Mammalian-Cell)