product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (PLCD1)
catalog :
MBS718827
quantity :
1 mg (E Coli Derived
price :
2705 USD
more info or order :
product information
catalog number :
MBS718827
products type :
Recombinant Protein
products full name :
Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (PLCD1)
products short name :
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (PLCD1)
other names :
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1; PLC-delta-1; phospholipase C-III; phosphoinositide phospholipase C-delta-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1; phospholipase C, delta 1; Phosphoinositide phospholipase C-delta-1; Phospholipase C-III; PLC-III; Phospholipase C-delta-1; PLC-delta-1
products gene name :
PLCD1
other gene names :
PLCD1; PLCD1; NDNC3; PLC-III; PLC-III; PLC-delta-1
uniprot entry name :
PLCD1_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-756
sequence length :
777
sequence :
MDSGRDFLTL HGLQDDEDLQ ALLKGSQLLK VKSSSWRRER FYKLQEDCKT IWQESRKVMR TPESQLFSIE DIQEVRMGHR TEGLEKFARD VPEDRCFSIV FKDQRNTLDL IAPSPADAQH WVLGLHKIIH HSGSMDQRQK LQHWIHSCLR KADKNKDNKM SFKELQNFLK ELNIQVDDSY ARKIFRECDH SQTDSLEDEE IEAFYKMLTQ RVEIDRTFAE AAGSGETLSV DQLVTFLQHQ QREEAAGPAL ALSLIERYEP SETAKAQRQM TKDGFLMYLL SADGSAFSLA HRRVYQDMGQ PLSHYLVSSS HNTYLLEDQL AGPSSTEAYI RALCKGCRCL ELDCWDGPNQ EPIIYHGYTF TSKILFCDVL RAIRDYAFKA SPYPVILSLE NHCTLEQQRV MARHLHAILG PMLLNRPLDG VTNSLPSPEQ LKGKILLKGK KLGGLLPPGG EGGPEATVVS DEDEAAEMED EAVRSRVQHK PKEDKLRLAQ ELSDMVIYCK SVHFGGFSSP GTPGQAFYEM ASFSENRALR LLQESGNGFV RHNVGHLSRI YPAGWRTDSS NYSPVEMWNG GCQIVALNFQ TPGPEMDVYQ GRFQDNGACG YVLKPAFLRD PNGTFNPRAL AQGPWWARKR LNIRVISGQQ LPKVNKNKNS IVDPKVTVEI HGVSRDVASR QTAVITNNGF NPWWDTEFAF EVVVPDLALI RFLVEDYDAS SKNDFIGQST IPLNSLKQGY RHVHLMSKNG DQHPSATLFV KISLQD
purity :
>90%
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info1 :
Tag Information: His tagged. Species: Homo sapiens (Human)
other info2 :
Storage Buffer: Tris-based buffer,50% glycerol. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ncbi gi num :
195972883
ncbi acc num :
NP_001124436.1
ncbi gb acc num :
NM_001130964.1
uniprot acc num :
P51178
ncbi mol weight :
88,135 Da
ncbi pathways :
Calcium Signaling Pathway 83050!!Calcium Signaling Pathway 459!!D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway 545326!!D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway 138940!!D-myo-inositol-5-phosphate Metabolism Pathway 545315!!D-myo-inositol-5-phosphate Metabolism Pathway 138601!!Inositol Phosphate Metabolism Pathway 82987!!Inositol Phosphate Metabolism Pathway 730320!!Inositol Phosphate Metabolism Pathway 362!!Inositol Phosphate Metabolism, PI= PIP2 = Ins(1,4,5)P3 = Ins(1,3,4,5)P4 Pathway 413400
ncbi summary :
This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
size :
1 mg (E Coli Derived)
price :
2705 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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