Recombinant Human Heterogeneous nuclear ribonucleoprotein M (HNRNPM) | MyBioSource MBS717726 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Heterogeneous nuclear ribonucleoprotein M (HNRNPM)

catalog :

MBS717726

quantity :

0.05 mg (E-Coli)

price :

180 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS717726

products type :

Recombinant Protein

products full name :

Recombinant Human Heterogeneous nuclear ribonucleoprotein M (HNRNPM)

products short name :

Heterogeneous nuclear ribonucleoprotein M (HNRNPM)

products name syn :

Heterogeneous nuclear ribonucleoprotein M; hnRNP M

other names :

heterogeneous nuclear ribonucleoprotein M isoform a; Heterogeneous nuclear ribonucleoprotein M; heterogeneous nuclear ribonucleoprotein M; CEA receptor; hnRNA-binding protein M4; N-acetylglucosamine receptor 1; heterogenous nuclear ribonucleoprotein M4; heterogeneous nuclear ribonucleoprotein M

products gene name :

HNRNPM

products gene name syn :

HNRNPM; HNRPM; NAGR1

other gene names :

HNRNPM; HNRNPM; CEAR; HNRPM; HTGR1; NAGR1; HNRPM4; HNRNPM4; hnRNP M; HNRPM; NAGR1; hnRNP M

uniprot entry name :

HNRPM_HUMAN

host :

E Coli or Yeast or Baculovirus or Mammalian Cell

sequence positions :

2-730; Full length.

sequence length :

730

sequence :

AAGVEAAAEVAATEIKMEEESGAPGVPSGNGAPGPKGEG
ERPAQNEKRKEKNIKRGGNRFEPYANPTKRYRAFITNIP
FDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVE
FKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAM
QKVMATTGGMGMGPGGPGMITIPPSILNNPNIPNEIIHA
LQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADI
LEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPM
HVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQ
PIDANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGMEGP
FGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGG
GGGGGSVPGIERMGPGIDRLGGAGMERMGAGLGHGMDRV
GSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSI
ERMGQTMERIGSGVERMGAGMGFGLERMAAPIDRVGQTI
ERMGSGVERMGPAIERMGLSMERMVPAGMGAGLERMGPV
MDRMATGLERMGANNLERMGLERMGANSLERMGLERMGA
NSLERMGPAMGPALGAGIERMGLAMGGGGGASFDRAIEM
ERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDF
TWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPE
VAERACRMMNGMKLSGREIDVRIDRNA

purity :

>90%

form :

Liquid containing glycerol; lyophilization may be available upon request.

storage stability :

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

other info1 :

Species: Homo sapiens (Human)

products description :

Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.

ncbi gi num :

14141152

ncbi acc num :

NP_005959.2

ncbi gb acc num :

NM_005968.4

uniprot acc num :

P52272

ncbi mol weight :

85kD

ncbi pathways :

Gene Expression Pathway (105937); Processing Of Capped Intron-Containing Pre-mRNA Pathway (160950); Spliceosome Pathway (125136); Spliceosome Pathway (124832); MRNA Splicing Pathway (105951); MRNA Splicing - Major Pathway (105952); MRNA Processing Pathway (198843)

ncbi summary :

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

uniprot summary :

hnRNP M: Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Nucleolus; Spliceosome; RNA-binding; Receptor, misc.; RNA splicing. Chromosomal Location of Human Ortholog: 19p13.2. Cellular Component: nucleoplasm; spliceosome; extracellular matrix; nuclear matrix; membrane; integral to plasma membrane; nucleolus; paraspeckles. Molecular Function: protein domain specific binding; protein binding; RNA binding; nucleotide binding. Biological Process: alternative nuclear mRNA splicing, via spliceosome; nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression

size1 :

0.05 mg (E-Coli)

price1 :

180 USD

size2 :

0.05 mg (Yeast)

price2 :

260

size3 :

0.2 mg (E-Coli)

price3 :

490

size4 :

0.2 mg (Yeast)

price4 :

600

size5 :

0.5 mg (E-Coli)

price5 :

715

more info or order :

MyBioSource product webpage