product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Bovine fibrinogen
catalog :
MBS717437
quantity :
1 mg
price :
200 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS717437
products type :
Native Protein
products full name :
Bovine fibrinogen
products short name :
fibrinogen
other names :
fibrinogen; Fibrinogen gamma-B chain; fibrinogen gamma-B chain; gamma'; fibrinogen, gamma polypeptide; fibrinogen gamma chain<; N/A
other gene names :
FGG; FGG; Gamma'
uniprot entry name :
FIBG_BOVIN
host :
Purified from pooled normal Bovine serum
purity :
>95% (SDS-PAGE)
form :
Liquid
storage stability :
Aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze / thaw cycles.
other info2 :
Storage Buffer: PBS
ncbi gi num :
350
ncbi acc num :
CAA33562.1
uniprot acc num :
P12799
ncbi mol weight :
50,244 Da
ncbi pathways :
Complement And Coagulation Cascades Pathway 84312!!Complement And Coagulation Cascades Pathway 484!!Staphylococcus Aureus Infection Pathway 172831!!Staphylococcus Aureus Infection Pathway 171867
uniprot summary :
Function: Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation. Subunit structure: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain . By similarity. Subcellular location: Secreted. Domain: A long coiled coil structure formed by 3 polypeptide chains connects the central nodule to the C-terminal domains (distal nodules). The long C-terminal ends of the alpha chains fold back, contributing a fourth strand to the coiled coil structure. Post-translational modification: Conversion of fibrinogen to fibrin is triggered by thrombin, which cleaves fibrinopeptides A and B from alpha and beta chains, and thus exposes the N-terminal polymerization sites responsible for the formation of the soft clot. The soft clot is converted into the hard clot by factor XIIIA which catalyzes the epsilon-(gamma-glutamyl)lysine cross-linking between gamma chains (stronger) and between alpha chains (weaker) of different monomers. Sequence similarities: Contains 1 fibrinogen C-terminal domain.
size :
1 mg
price :
200 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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