product summary
Loading...
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Phosphoglycerate kinase 1
catalog :
MBS717266
quantity :
0.05 mg (E-Coli)
price :
180 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS717266
products type :
Recombinant Protein
products full name :
Recombinant Human Phosphoglycerate kinase 1
products short name :
Phosphoglycerate kinase 1
products name syn :
Cell migration-inducing gene 10 protein; Primer recognition protein 2; PRP 2
other names :
phosphoglycerate kinase 1; Phosphoglycerate kinase 1; phosphoglycerate kinase 1; phosphoglycerate kinase 1; Cell migration-inducing gene 10 protein; Primer recognition protein 2; PRP 2
products gene name :
PGK1
products gene name syn :
PGKA; MIG10; OK; SW-cl.110
other gene names :
PGK1; PGK1; PGKA; MIG10; HEL-S-68p; PGKA; PRP 2
uniprot entry name :
PGK1_HUMAN
host :
E Coli
sequence positions :
25-417
sequence length :
417
sequence :
FNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSH
LGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGP
EVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVK
AEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN
LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVAD
KIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLF
DEEGAKIVKDLMSKAEKNGVK
purity :
Greater than 90% as determined by SDS-PAGE.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products categories :
Metabolism
products description :
In addition to its role as a glycolytic enzyme, it ses that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein).
products references :
Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase.Michelson A.M., Markham A.F., Orkin S.H.Proc. Natl. Acad. Sci. U.S.A. 80:472-476(1983)
ncbi gi num :
4505763
ncbi acc num :
NP_000282.1
ncbi gb acc num :
NM_000291.3
uniprot acc num :
P00558
ncbi mol weight :
69.3kD
ncbi pathways :
Biosynthesis Of Amino Acids Pathway (790012); Biosynthesis Of Amino Acids Pathway (795174); Carbon Metabolism Pathway (814926); Carbon Metabolism Pathway (817567); Gluconeogenesis Pathway (1269961); Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway (413342); Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway (468196); Glucose Metabolism Pathway (1269959); Glycolysis Pathway (1269960); Glycolysis (Embden-Meyerhof Pathway), Glucose = Pyruvate (413340)
ncbi summary :
The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]
uniprot summary :
PGK1: an apparent multifunctional protein. A glycolytic enzyme and a polymerase alpha cofactor protein (primer recognition protein). Protein type: Kinase, other; EC 2.7.2.3; Carbohydrate Metabolism - glycolysis and gluconeogenesis. Chromosomal Location of Human Ortholog: Xq13.3. Cellular Component: cytosol; lipid raft; membrane. Molecular Function: ATP binding; phosphoglycerate kinase activity; protein binding. Biological Process: carbohydrate metabolic process; epithelial cell differentiation; gluconeogenesis; glucose metabolic process; phosphorylation. Disease: Phosphoglycerate Kinase 1 Deficiency
size1 :
0.05 mg (E-Coli)
price1 :
180 USD
size2 :
0.2 mg (E-Coli)
price2 :
410
size3 :
0.5 mg (E-Coli)
price3 :
665
size4 :
1 mg (E-Coli)
price4 :
1050
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!