product summary
Loading...
company name :
MyBioSource
product type :
protein
product name :
Recombinant human L-lactate dehydrogenase A chain
catalog :
MBS717238
quantity :
0.05 mg
price :
195 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS717238
products type :
Recombinant Protein
products full name :
Recombinant human L-lactate dehydrogenase A chain
products short name :
L-lactate dehydrogenase A chain
products name syn :
Recombinant human L-lactate dehydrogenase A chain protein
other names :
Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 1, mRNA; L-lactate dehydrogenase A chain; L-lactate dehydrogenase A chain; LDH-A; LDH-M; LDH muscle subunit; lactate dehydrogenase M; proliferation-inducing gene 19; renal carcinoma antigen NY-REN-59; cell proliferation-inducing gene 19 protein; lactate dehydrogenase A; Cell proliferation-inducing gene 19 protein; LDH muscle subunit; LDH-M; Renal carcinoma antigen NY-REN-59
other gene names :
LDHA; LDHA; LDH1; LDHM; GSD11; PIG19; LDH-A; LDH-M
uniprot entry name :
LDHA_HUMAN
host :
E Coli
sequence :
KDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKD
LADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKD
YNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFII
PNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIG
SGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVP
VWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESA
YEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMI
KGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARL
KKSADTL
purity :
0.95
storage stability :
Store at -20 degree C. For extended storage, conserve at -20 or -80 degree C.
other info2 :
Storage Buffer: PBS pH 7.4, 50% glycerol
products description :
(S)-lactate + NAD+ = pyruvate + NADH.
products references :
[1] "Nucleotide sequences of the cDNA and an intronless pseudogene for human lactate dehydrogenase-A isozyme.
ncbi gi num :
207028465
ncbi acc num :
NP_005557.1
ncbi gb acc num :
NM_005566.3
uniprot acc num :
P00338
ncbi mol weight :
62 KD
ncbi pathways :
Cysteine And Methionine Metabolism Pathway 104488!!Cysteine And Methionine Metabolism Pathway 103421!!Glycolysis / Gluconeogenesis Pathway 82926!!Glycolysis / Gluconeogenesis Pathway 287!!Glycolysis And Gluconeogenesis Pathway 198814!!HIF-1-alpha Transcription Factor Network Pathway 138045!!Metabolism Pathway 477135!!Propanoate Metabolism Pathway 83004!!Propanoate Metabolism Pathway 387!!Pyruvate Metabolism Pathway 106205
ncbi summary :
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008]
uniprot summary :
Catalytic activity: (S)-lactate + NAD+ = pyruvate + NADH. Pathway: Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1. Subunit structure: Homotetramer. Ref.22. Subcellular location: Cytoplasm. Post-translational modification: ISGylated. Ref.15. Involvement in disease: Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [. MIM:612933]. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue. Ref.13. Sequence similarities: Belongs to the LDH/MDH superfamily. LDH family.
size :
0.05 mg
price :
195 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!