catalog number :
MBS717155
products type :
Recombinant Protein
products full name :
Recombinant Human Eukaryotic initiation factor 4A-II (EIF4A2)
products short name :
[Eukaryotic initiation factor 4A-II (EIF4A2)]
other names :
[eukaryotic initiation factor 4A-II; Eukaryotic initiation factor 4A-II; eukaryotic initiation factor 4A-II; eukaryotic translation initiation factor 4A2; ATP-dependent RNA helicase eIF4A-2]
products gene name :
[EIF4A2]
products gene name syn :
[EIF4A2]
other gene names :
[EIF4A2; EIF4A2; DDX2B; EIF4A; EIF4F; BM-010; eIF4A-II; eIF-4A-II; DDX2B; EIF4F; eIF-4A-II; eIF4A-II]
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
[1-407. Full Length]
sequence :
MSGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMN
LKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQ
SGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQI
QKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIV
VGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKD
QIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIR
ILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTI
TQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKER
DVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLP
TNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIET
FYNTTVEEMPMNVADLI
form :
Liquid containing glycerol
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
image1 heading :
SDS-PAGE
other info1 :
Species: Human
other info2 :
Storage Buffer: Tris-based buffer, 50% glycerol. Production Note: Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.
ncbi acc num :
NP_001958.2
ncbi gb acc num :
NM_001967.3
ncbi mol weight :
46,489 Da
ncbi pathways :
Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway (1268683); Antiviral Mechanism By IFN-stimulated Genes Pathway (1269316); Cap-dependent Translation Initiation Pathway (1268680); Cytokine Signaling In Immune System Pathway (1269310); Deadenylation Of MRNA Pathway (1269713); Deadenylation-dependent MRNA Decay Pathway (1269712); Eukaryotic Translation Initiation Pathway (1268679); GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway (1268686); Gene Expression Pathway (1269649); ISG15 Antiviral Mechanism Pathway (1269317)
uniprot summary :
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.