catalog number :
MBS717140
products type :
Recombinant Protein
products full name :
Recombinant Human 60S ribosomal protein L27
products short name :
60S ribosomal protein L27
other names :
60S ribosomal protein L27; 60S ribosomal protein L27; 60S ribosomal protein L27; ribosomal protein L27
products gene name :
RPL27
other gene names :
RPL27; RPL27; L27
uniprot entry name :
RL27_HUMAN
sequence positions :
2-136
sequence :
GKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSH
ALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNH
LMPTRYSVDIPLDKTVVNKDVFRDPALKRKARREAKVKF
EERYKTGKNKWFFQKLRF
purity :
Greater than 90% as determined by SDS-PAGE.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products categories :
Epigenetics and Nuclear Signaling
products references :
Cloning and nucleotide sequence of a full length cDNA encoding ribosomal protein L27 from human fetal kidney.Gallagher R.A., McClean P.M., Malik A.N.Biochim. Biophys. Acta 1217:329-332(1994)
The human ribosomal protein genes
sequencing and comparative analysis of 73 genes.Yoshihama M., Uechi T., Asakawa S., Kawasaki K., Kato S., Higa S., Maeda N., Minoshima S., Tanaka T., Shimizu N., Kenmochi N.Genome Res. 12:379-390(2002)
Bhat K.S.
Lysine acetylation targets protein complexes and co-regulates major cellular functions.Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.Science 325:834-840(2009)
Initial characterization of the human central proteome.Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011)
N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012)
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014)
Structures of the human and Drosophila 80S ribosome.Anger A.M., Armache J.P., Berninghausen O., Habeck M., Subklewe M., Wilson D.N., Beckmann R.Nature 497:80-85(2013)
ncbi acc num :
NP_000979.1
ncbi gb acc num :
NM_000988.3
ncbi pathways :
Cap-dependent Translation Initiation Pathway (1268680); Cytoplasmic Ribosomal Proteins Pathway (198853); Disease Pathway (1268854); Eukaryotic Translation Elongation Pathway (1268690); Eukaryotic Translation Initiation Pathway (1268679); Eukaryotic Translation Termination Pathway (1268692); Formation Of A Pool Of Free 40S Subunits Pathway (1268681); GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway (1268686); Gene Expression Pathway (1269649); Infectious Disease Pathway (1269056)
ncbi summary :
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L27E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
uniprot summary :
RPL27: a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L27E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]. Protein type: Ribosomal; Translation. Chromosomal Location of Human Ortholog: 17q21. Cellular Component: cytosol; focal adhesion; membrane; nucleus; ribonucleoprotein complex; ribosome. Molecular Function: structural constituent of ribosome. Biological Process: cellular protein metabolic process; gene expression; mRNA catabolic process, nonsense-mediated decay; selenium metabolic process; selenocysteine metabolic process; SRP-dependent cotranslational protein targeting to membrane; translation; translational elongation; translational initiation; translational termination; viral infectious cycle; viral reproduction; viral transcription