product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant human 6-phosphogluconate dehydrogenase, decarboxylating
catalog :
MBS717103
quantity :
0.05 mg
price :
195 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS717103
products type :
Recombinant Protein
products full name :
Recombinant human 6-phosphogluconate dehydrogenase, decarboxylating
products short name :
6-phosphogluconate dehydrogenase, decarboxylating
products name syn :
Recombinant human 6-phosphogluconate dehydrogenase; decarboxylating protein
other names :
Homo sapiens phosphogluconate dehydrogenase (PGD), mRNA; 6-phosphogluconate dehydrogenase, decarboxylating; 6-phosphogluconate dehydrogenase, decarboxylating; phosphogluconate dehydrogenase
other gene names :
PGD; PGD; 6PGD; PGDH
uniprot entry name :
6PGD_HUMAN
host :
E Coli
sequence :
ADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDF
LANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAV
DDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKG
ILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQG
IAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLI
CEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITA
NILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGV
PVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGD
KKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLN
YGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDD
FFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDG
YRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTG
HGGTVSSSSYNA
purity :
0.95
storage stability :
Store at -20 degree C. For extended storage, conserve at -20 or -80 degree C.
other info1 :
Tag Information: GST tagged
other info2 :
Storage Buffer: PBS pH 7.4, 50% glycerol
products description :
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH
products references :
[1] "Identification of a cDNA encoding 6-phosphogluconate dehydrogenase from a human heart cDNA library.
ncbi gi num :
40068517
ncbi acc num :
NP_002622.2
ncbi gb acc num :
NM_002631.2
uniprot acc num :
P52209
ncbi mol weight :
80 KD
ncbi pathways :
Glutathione Metabolism Pathway 82973!!Glutathione Metabolism Pathway 343!!Metabolism Pathway 477135!!Metabolism Of Carbohydrates Pathway 106196!!Pentose Phosphate Pathway 198829!!Pentose Phosphate Pathway 82928!!Pentose Phosphate Pathway 289!!Pentose Phosphate Pathway (Pentose Phosphate Cycle) 413343!!Pentose Phosphate Pathway (Pentose Phosphate Cycle) 468197!!Pentose Phosphate Pathway (hexose Monophosphate Shunt) 106220
ncbi summary :
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH . By similarity. Catalytic activity: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH. Pathway: Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3. Subunit structure: Homodimer. Ref.5. Subcellular location: Cytoplasm . By similarity. Sequence similarities: Belongs to the 6-phosphogluconate dehydrogenase family.
size :
0.05 mg
price :
195 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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