product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant human Interferon-induced transmembrane protein 1
catalog :
MBS717091
quantity :
0.05 mg
price :
195 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS717091
products type :
Recombinant Protein
products full name :
Recombinant human Interferon-induced transmembrane protein 1
products short name :
Interferon-induced transmembrane protein 1
products name syn :
Recombinant human Interferon-induced transmembrane protein 1 protein
other names :
Homo sapiens interferon induced transmembrane protein 1 (IFITM1), mRNA; Interferon-induced transmembrane protein 1; interferon-induced transmembrane protein 1; leu-13 antigen; interferon-induced protein 17; dispanin subfamily A member 2a; interferon-inducible protein 9-27; interferon induced transmembrane protein 1; Dispanin subfamily A member 2a; DSPA2a; Interferon-induced protein 17; Interferon-inducible protein 9-27; Leu-13 antigen
other gene names :
IFITM1; IFITM1; 9-27; CD225; IFI17; LEU13; DSPA2a; CD225; IFI17; DSPA2a
uniprot entry name :
IFM1_HUMAN
host :
E Coli
sequence :
MHKEEHEVAVLGAPPSTILPRSTVINIHSETSVPDH
purity :
0.95
storage stability :
Store at -20 degree C. For extended storage, conserve at -20 or -80 degree C.
other info1 :
Tag Information: GST-tagged
other info2 :
Storage Buffer: PBS pH 7.4, 50% glycerol
products description :
IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.
products references :
[1] "A single DNA response element can confer inducibility by both alpha- and gamma-interferons.
ncbi gi num :
150010588
ncbi acc num :
NP_003632.3
ncbi gb acc num :
NM_003641.3
uniprot acc num :
P13164
ncbi mol weight :
30 KD
ncbi pathways :
Adaptive Immune System Pathway 366160!!B Cell Receptor Signaling Pathway 83081!!B Cell Receptor Signaling Pathway 492!!Cytokine Signaling In Immune System Pathway 366171!!Immune System Pathway 106386!!Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway 106413!!Interferon Signaling Pathway 187103!!Interferon Alpha/beta Signaling Pathway 187104
uniprot summary :
Function: IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals. Ref.8 Ref.10. Subunit structure: Interacts with CAV1; this interaction enhances the ability of CAV1 in inhibiting ERK activation. Ref.9. Subcellular location: Cell membrane; Multi-pass membrane protein Ref.9. Induction: By IFN-alpha and IFNG/IFN-gamma. Post-translational modification: Palmitoylation on membrane-proximal cysteines controls clustering in membrane compartments and antiviral activity against influenza virus . By similarity. Sequence similarities: Belongs to the CD225/Dispanin family.
size :
0.05 mg
price :
195 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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