catalog number :
MBS717077
products type :
Recombinant Protein
products full name :
Recombinant human Fatty acid-binding protein, heart
products short name :
Fatty acid-binding protein, heart
products name syn :
Recombinant human Fatty acid-binding protein; heart protein
other names :
Homo sapiens fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) (FABP3), mRNA; Fatty acid-binding protein, heart; fatty acid-binding protein, heart; fatty acid binding protein 11; mammary-derived growth inhibitor; muscle fatty acid-binding protein; Fatty acid-binding protein 3, muscle; heart-type fatty acid-binding protein; fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor); Fatty acid-binding protein 3; Heart-type fatty acid-binding protein; H-FABP; Mammary-derived growth inhibitor; MDGI; Muscle fatty acid-binding protein
other gene names :
FABP3; FABP3; MDGI; FABP11; H-FABP; M-FABP; O-FABP; FABP11; MDGI; H-FABP; MDGI; M-FABP
uniprot entry name :
FABPH_HUMAN
sequence :
VDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPT
TIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDR
KVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTL
THGTAVCTRTYEKEA
storage stability :
Store at -20 degree C. For extended storage, conserve at -20 or -80 degree C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
products description :
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
products references :
[1] "Cloning of the cDNA encoding human skeletal-muscle fatty-acid-binding protein, its peptide sequence and chromosomal localization.
ncbi acc num :
NP_004093.1
ncbi gb acc num :
NM_004102.3
ncbi pathways :
PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450)
ncbi summary :
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. Subcellular location: Cytoplasm. Domain: Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior. Sequence similarities: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.