catalog number :
MBS717055
products type :
Recombinant Protein
products full name :
Recombinant Rabbit Triadin protein
products short name :
Triadin
other names :
Oryctolagus cuniculus triadin (TRDN), mRNA; Triadin; triadin; junctional sarcoplasmic reticulum glycoprotein
other gene names :
TRDN; TRDN
uniprot entry name :
TRDN_RABIT
sequence :
DLVDYKNFSA SSIAKMGSDP LKLVHDAVEE TTDWIYGFFS LLSDIISSDG DEEDDEGDED TAKGEIEEPP LKRKDIHKEK IEKQEKPERK IPTKVVHKEK EKEKEKVKEK EKPEKKATHK EKLEKKEKPE TKTVTKEEKK ARTKEKIEEK TKKEVKGVKQ EKVKQTVAKA KEVQKTPKPK EKESKETAAV SKQEQKDQYA FCRYMIDIFV HGDLKPGQSP AIPPPSPTEQ ASRPTPALPT PEEKEGEKKK AEKKVTTETK KKAEKEDAKK KSEKETDIDM KKKEPGKSPD TKPGTVKVTT QAATKKDEKK EDSKKAKKPA EEQPKGKKQE KKEKHEEPAK STKKEHAAPS EKQAKAKIER KEEVSAASTK KAVPAKKEEK TTKTVEQETR KEKPGKISSV LKDKELTKEK EVKVPASLKE KGSETKKDEK TSKPEPQIKK EEKPGKEVKP KPPQPQIKKE EKPEQDIMKP EKTALHGKPE EKVLKQVKAV TTEKHVKPKP AKKAEHQEKE PPSIKTDKPK STSKGMPEVT ESGKKKIEKS EKEIKVPARR ESHQLQNVTK AEKPARGSKE GFEDVPASKK AKEEAEEVSS TKKQKSPISF FQCVYLDGYN GYGFQFPVTP AQYPGESSGK PNSPGPKQ
storage stability :
Repeated freezing and thawing is not recommended.Store working aliquots at 4 degree C for up to one week. Store at -20 degree C, for extended storage, store at -20 degree C or -80 degree C.
tested application :
SDS-PAGE, ELISA, Western Blot
products description :
May be involved in anchoring calsequestrin to the junctional sarcoplasmic reticulum and allowing its functional coupling with the ryanodine receptor.
products references :
[1] "Primary structure and topological analysis of a skeletal muscle-specific junctional sarcoplasmic reticulum glycoprotein (triadin)."Knudson C.M., Stang K.K., Moomaw C.R., Slaughter C.A., Campbell K.P.J.Biol.Chem.268:12646-12654(1993) [PubMed: 7685347] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE (ISOFORMS SKELETAL 1; SKELETAL 2 AND SKELETAL 3).Strain: New Zealand white.Tissue: Skeletal muscle. [2] "Structural diversity of triadin in skeletal muscle and evidence of its existence in heart."Peng M., Fan H., Kirley T.L., Caswell A.H., Schwartz A.FEBS Lett.348:17-20(1994) [PubMed: 8026576] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE (ISOFORMS SKELETAL 1; SKELETAL 2 AND SKELETAL 3).Tissue: Skeletal muscle. [3] "Biochemical characterization and molecular cloning of cardiac triadin."Guo W., Jorgensen A.O., Jones L.R., Campbell K.P.J.Biol.Chem.271:458-465(1996) [PubMed: 8550602] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE (ISOFORMS CARDIAC 1; CARDIAC 2 AND CARDIAC 3).Tissue: Heart muscle. [4] "Disulfide bonds, N-glycosylation and transmembrane topology of skeletal muscle triadin."Fan H., Brandt N.R., Caswell A.H.Biochemistry 34:14902-14908(1995) [PubMed: 7578102] [Abstract] Cited for: GLYCOSYLATION AT ASN-625, SUBUNIT.
ncbi acc num :
NP_001076212.1
ncbi gb acc num :
NM_001082743.1
uniprot summary :
Function: May be involved in anchoring calsequestrin to the junctional sarcoplasmic reticulum and allowing its functional coupling with the ryanodine receptor.Subunit structure: Homooligomer of variable subunit number; disulfide-linked. Ref.4Subcellular location: Sarcoplasmic reticulum membrane; Single-pass type II membrane protein. Tissue specificity: Skeletal and cardiac muscle.