protein

Bovine Transferrin

MBS717013

10 mg

345 USD

Native Protein

Bovine Transferrin

Transferrin

Serotransferrin; Beta-1 metal-binding globulin; Siderophilin

transferrin; Serotransferrin; serotransferrin; siderophilin; beta-1 metal-binding globulin; transferrin; Beta-1 metal-binding globulin; Siderophilin

TF; TF; TFQTL1; PRO1557; PRO2086; Transferrin

TRFE_HUMAN

Purified from Bovine Serum

>95%(SDS-PAGE)

Liquid

Aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze / thaw cycles.

ELISA (EIA), Western Blot (WB)

Peptide: Full length native Bovine Transferrin

Storage Buffer: PBS,pH7.4 ,50%glycerol

Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

248648

AAB22049.1

P02787

77,064 Da

EPHB Forward Signaling Pathway (138047); HIF-1-alpha Transcription Factor Network Pathway (138045); Hemostasis Pathway (106028); Iron Uptake And Transport Pathway (187191); Mineral Absorption Pathway (212237); Mineral Absorption Pathway (212220); Platelet Activation, Signaling And Aggregation Pathway (106034); Platelet Degranulation Pathway (106050); Response To Elevated Platelet Cytosolic Ca2+ Pathway (106048); Transferrin Endocytosis And Recycling Pathway (187192)

This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]

Function: Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Subunit structure: Monomer. Subcellular location: Secreted. Tissue specificity: Expressed by the liver and secreted in plasma. Polymorphism: Different polymorphic variants of transferrin are known. The sequence shown is the predominant electrophoretic variant (C1 or TF*C1). Involvement in disease: Defects in TF are the cause of atransferrinemia (ATRAF) [. MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. Ref.4 Ref.39. Sequence similarities: Belongs to the transferrin family.Contains 2 transferrin-like domains. Sequence caution: The sequence AAF22007.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

10 mg

345 USD