catalog number :
MBS716814
products full name :
Rabbit anti-human phosphoribosyl pyrophosphate synthetase 1 polyclonal Antibody
products short name :
phosphoribosyl pyrophosphate synthetase 1
products name syn :
phosphoribosyl pyrophosphate synthetase 1; PRPS1; ARTS; CMTX5; KIAA0967; PPRibP; PRSI
other names :
Phosphoribosyl pyrophosphate synthetase 1; Ribose-phosphate pyrophosphokinase 1; ribose-phosphate pyrophosphokinase 1; deafness 2, perceptive, congenital; ribose-phosphate diphosphokinase 1; phosphoribosyl pyrophosphate synthase I; deafness, X-linked 2, perceptive, congenital; dJ1070B1.2 (phosphoribosyl pyrophosphate synthetase 1); phosphoribosyl pyrophosphate synthetase 1; PPRibP; Phosphoribosyl pyrophosphate synthase I; PRS-I
other gene names :
PRPS1; PRPS1; ARTS; DFN2; PRSI; CMTX5; DFNX1; PRS-I; PPRibP; PRS-I
uniprot entry name :
PRPS1_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
other info1 :
Immunogen: Human PRPS1
other info2 :
Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAH01605.1
ncbi mol weight :
27,526 Da
ncbi pathways :
5-Phosphoribose 1-diphosphate Biosynthesis Pathway 106221!!Biosynthesis Of Amino Acids Pathway 790012!!Biosynthesis Of Amino Acids Pathway 795174!!Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Disease Pathway 530764!!Glycogen Storage Diseases Pathway 980468!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Carbohydrates Pathway 106196
ncbi summary :
This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]