product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human asialoglycoprotein receptor 1 polyclonal Antibody
catalog :
MBS716633
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS716633
products type :
Antibody
products full name :
Rabbit anti-human asialoglycoprotein receptor 1 polyclonal Antibody
products short name :
asialoglycoprotein receptor 1
products name syn :
asialoglycoprotein receptor 1; ASGR1; ASGPR; CLEC4H1; Hs.12056
other names :
Asialoglycoprotein receptor 1; Asialoglycoprotein receptor 1; asialoglycoprotein receptor 1; hepatic lectin H1; C-type lectin domain family 4 member H1; asialoglycoprotein receptor 1; C-type lectin domain family 4 member H1; Hepatic lectin H1; HL-1
other gene names :
ASGR1; ASGR1; HL-1; ASGPR; ASGPR1; CLEC4H1; CLEC4H1; ASGP-R 1; ASGPR 1; HL-1
uniprot entry name :
ASGR1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
291
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human ASGR1
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
18149183
ncbi acc num :
BAB83508.1
ncbi mol weight :
29,144 Da
ncbi pathways :
Thyroid Hormone Synthesis Pathway (835410); Thyroid Hormone Synthesis Pathway (839541)
ncbi summary :
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
uniprot summary :
ASGR1: Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 17p13.2. Cellular Component: integral to plasma membrane; extracellular region. Molecular Function: protein binding; protein homodimerization activity; metal ion binding; asialoglycoprotein receptor activity; carbohydrate binding. Biological Process: receptor-mediated endocytosis; cellular response to extracellular stimulus
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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