catalog number :
MBS716580
products full name :
Rabbit anti-human ATP-binding cassette, sub-family B (MDR/TAP), member 7 polyclonal Antibody
products short name :
ATP-binding cassette, sub-family B (MDR/TAP), member 7
products name syn :
ATP-binding cassette; sub-family B (MDR/TAP); member 7; ABCB7; ABC7; ASAT; Atm1p; EST140535
other names :
ATP-binding cassette, sub-family B (MDR/TAP), member 7; ATP-binding cassette sub-family B member 7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial; ABC transporter 7 protein; ATP-binding cassette transporter 7; ATP-binding cassette, sub-family B (MDR/TAP), member 7; ATP-binding cassette transporter 7; ABC transporter 7 protein
other gene names :
ABCB7; ABCB7; ABC7; ASAT; Atm1p; EST140535; ABC7; ABC transporter 7 protein
uniprot entry name :
ABCB7_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human ABCB7
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAH06323.1
ncbi mol weight :
78,160 Da
ncbi pathways :
ABC Transporters Pathway 83035!!ABC Transporters Pathway 436!!ABC-family Proteins Mediated Transport Pathway 106573!!Cytosolic Iron-sulfur Cluster Assembly Pathway 771576!!Metabolism Pathway 477135!!Mitochondrial ABC Transporters Pathway 477113!!Transmembrane Transport Of Small Molecules Pathway 106572
ncbi summary :
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]