Rabbit anti-human ST3 beta-galactoside alpha-2, 3-sialyltransferase 6 polyclonal Antibody | MyBioSource MBS716546 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit anti-human ST3 beta-galactoside alpha-2, 3-sialyltransferase 6 polyclonal Antibody

catalog :

MBS716546

quantity :

0.05 mL

price :

375 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS716546

products type :

Antibody

products full name :

Rabbit anti-human ST3 beta-galactoside alpha-2, 3-sialyltransferase 6 polyclonal Antibody

products short name :

ST3 beta-galactoside alpha-2, 3-sialyltransferase 6

products name syn :

ST3 beta-galactoside alpha-2,3-sialyltransferase 6;ST3GAL6;SIAT10;ST3GALVI

other names :

ST3 beta-galactoside alpha-2,3-sialyltransferase 6; Type 2 lactosamine alpha-2,3-sialyltransferase; type 2 lactosamine alpha-2,3-sialyltransferase; alpha2,3-sialyltransferase ST3Gal VI; sialyltransferase 10 (alpha-2,3-sialyltransferase VI); CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI; ST3 beta-galactoside alpha-2,3-sialyltransferase 6; CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI; ST3Gal VI; ST3GalVI; Sialyltransferase 10

other gene names :

ST3GAL6; ST3GAL6; SIAT10; ST3GALVI; SIAT10; ST3GalVI

uniprot entry name :

SIA10_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human,Mouse,Rat; Other species are not tested. Please decide the specificity by homology.

sequence length :

331

purity :

Antigen Affinity Purified

form :

Liquid

storage stability :

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

tested application :

ELISA (EIA), Western Blot (WB)

app notes :

ELISA; Use at an assay dependent dilution. WB : 1:500-1:5000 (Recommender dilution). Positive WB detected in: Human placenta tissue, human heart tissue

other info1 :

Conjugate : Non-conjugated

other info2 :

Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

products description :

Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1.

ncbi gi num :

23271058

ncbi acc num :

AAH23312.1

ncbi pathways :

Asparagine N-linked Glycosylation Pathway (161013); Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway (161014); Disease Pathway (530764); Glycogen Storage Diseases Pathway (980468); Glycosaminoglycan Metabolism Pathway (645297); Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway (82995); Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway (370); Keratan Sulfate Biosynthesis Pathway (645302); Keratan Sulfate/keratin Metabolism Pathway (645301); MPS I - Hurler Syndrome Pathway (685537)

ncbi summary :

The protein encoded by this gene is a member of the sialyltransferase family. Members of this family are enzymes that transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. This protein has high specificity for neolactotetraosylceramide and neolactohexaosylceramide as glycolipid substrates and may contribute to the formation of selectin ligands and sialyl Lewis X, a carbohydrate important for cell-to-cell recognition and a blood group antigen. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Sep 2012]

uniprot summary :

ST3GAL6: Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1. Belongs to the glycosyltransferase 29 family. Protein type: Membrane protein, integral; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; EC 2.4.99.-; Transferase. Chromosomal Location of Human Ortholog: 3q12.1. Cellular Component: Golgi membrane; integral to membrane; integral to Golgi membrane. Biological Process: keratan sulfate metabolic process; glycolipid metabolic process; cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; glycosaminoglycan metabolic process; keratan sulfate biosynthetic process; carbohydrate metabolic process; protein modification process; pathogenesis; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification; oligosaccharide metabolic process

size1 :

0.05 mL

price1 :

375 USD

size2 :

0.15 mL

price2 :

715

more info or order :

MyBioSource product webpage