product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human heparan sulfate 2-O-sulfotransferase 1 polyclonal Antibody
catalog :
MBS716512
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS716512
products type :
Antibody
products full name :
Rabbit anti-human heparan sulfate 2-O-sulfotransferase 1 polyclonal Antibody
products short name :
heparan sulfate 2-O-sulfotransferase 1
products name syn :
heparan sulfate 2-O-sulfotransferase 1; HS2ST1; FLJ11317; KIAA0448; MGC131986; dJ604K5.2
other names :
heparan sulfate 2-O-sulfotransferase 1 isoform 1; Heparan sulfate 2-O-sulfotransferase 1; heparan sulfate 2-O-sulfotransferase 1; 2OST; heparan sulfate 2-O-sulfotransferase 1
other gene names :
HS2ST1; HS2ST1; dJ604K5.2; HS2ST; KIAA0448; 2-O-sulfotransferase; 2OST
uniprot entry name :
HS2ST_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
356
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human HS2ST1
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
6912420
ncbi acc num :
NP_036394.1
ncbi gb acc num :
NM_012262.3
ncbi mol weight :
26,757 Da
ncbi pathways :
Disease Pathway (530764); Glycogen Storage Diseases Pathway (980468); Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway (82984); Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway (358); Glycosaminoglycan Metabolism Pathway (645297); HS-GAG Biosynthesis Pathway (645306); Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway (645304); MPS I - Hurler Syndrome Pathway (685537); MPS II - Hunter Syndrome Pathway (685538); MPS IIIA - Sanfilippo Syndrome A Pathway (685539)
ncbi summary :
Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Aug 2008]
uniprot summary :
HS2ST1: Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high- affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues. Belongs to the sulfotransferase 3 family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; EC 2.8.2.-; Transferase; Glycan Metabolism - heparan sulfate biosynthesis; Membrane protein, integral. Chromosomal Location of Human Ortholog: 1p22.3. Cellular Component: Golgi membrane; membrane; integral to membrane. Molecular Function: sulfotransferase activity. Biological Process: glycosaminoglycan biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; pathogenesis
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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