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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human myomesin 1, 185kDa polyclonal Antibody
catalog :
MBS716354
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS716354
products type :
Antibody
products full name :
Rabbit anti-human myomesin 1, 185kDa polyclonal Antibody
products short name :
myomesin 1
products name syn :
myomesin 1; 185kDa; MYOM1; MGC134946; MGC134947; SKELEMIN
other names :
myomesin 1; Myomesin-1; myomesin-1; EH-myomesin; myomesin 1, 185kDa; myomesin family member 1; myomesin 1 (skelemin) 185kDa; myomesin (M-protein) 1 (190kD); 190 kDa titin-associated protein; 190 kDa connectin-associated protein; myomesin 1; 190 kDa connectin-associated protein; 190 kDa titin-associated protein; Myomesin family member 1
other gene names :
MYOM1; MYOM1; SKELEMIN
uniprot entry name :
MYOM1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human,Mouse,Rat; Other species are not tested. Please decide the specificity by homology.
sequence length :
1685
purity :
Antigen Affinity Purified
form :
Liquid
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
ELISA:Use at an assay dependent dilution. WB : 1:200-1:2000. IHC : 1:20-1:200 (Recommender dilutions) . Positive IHC detected in: Human skeletal muscle tissue, human heart tissue. Positive WB detected in: Mouse skeletal muscle tissue, mouse brain tissue, SKOV-3 cells
other info1 :
Immunogen: Human MYOM1-Specific. Conjugate: Non-conjugated
other info2 :
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
products description :
Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.
ncbi gi num :
48994190
ncbi acc num :
CAF18565.1
uniprot acc num :
P52179
ncbi pathways :
Striated Muscle Contraction Pathway (198903)
ncbi summary :
The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
uniprot summary :
myomesin 1: Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 18p11.31. Cellular Component: striated muscle thick filament; M band. Molecular Function: identical protein binding; protein binding; protein homodimerization activity; structural constituent of muscle. Biological Process: muscle contraction
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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