catalog number :
MBS716261
products full name :
Rabbit anti-human solute carrier family 39 (zinc transporter), member 8 polyclonal Antibody
products short name :
solute carrier family 39 (zinc transporter), member 8
products name syn :
solute carrier family 39 (zinc transporter); member 8; SLC39A8; BIGM103; LZT-Hs6; PP3105; ZIP8
other names :
solute carrier family 39 (zinc transporter), member 8, isoform CRA_b; Zinc transporter ZIP8; zinc transporter ZIP8; ZIP-8; Zrt- and Irt-like protein 8; solute carrier family 39 member 8; LIV-1 subfamily of ZIP zinc transporter 6; BCG induced integral membrane protein BIGM103; solute carrier family 39 (metal ion transporter), member 8; BCG-induced integral membrane protein in monocyte clone 103 protein; solute carrier family 39 (zinc transporter), member 8; BCG-induced integral membrane protein in monocyte clone 103 protein; LIV-1 subfamily of ZIP zinc transporter 6; LZT-Hs6; Solute carrier family 39 member 8; Zrt- and Irt-like protein 8; ZIP-8
other gene names :
SLC39A8; SLC39A8; ZIP8; PP3105; BIGM103; LZT-Hs6; BIGM103; ZIP8; LZT-Hs6; ZIP-8
uniprot entry name :
S39A8_HUMAN
reactivity :
Human, Mouse
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
other info1 :
Immunogen: Human SLC39A8
other info2 :
Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
EAX06132.1
ncbi mol weight :
48,089 Da
ncbi pathways :
Metal Ion SLC Transporters Pathway (161066); SLC-mediated Transmembrane Transport Pathway (119558); Transmembrane Transport Of Small Molecules Pathway (106572); Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway (119571); Zinc Influx Into Cells By The SLC39 Gene Family Pathway (161069); Zinc Transporters Pathway (161067)
ncbi summary :
This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008]
uniprot summary :
SLC39A8: Acts as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral; Transporter. Chromosomal Location of Human Ortholog: 4q24. Cellular Component: integral to membrane; plasma membrane. Molecular Function: metal ion transmembrane transporter activity. Biological Process: zinc ion transport; transmembrane transport